USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes
Ubiquitin specific protease (USP) 2 is a multifunctional deubiquitinating enzyme. USP2 modulates cell cycle progression, and therefore carcinogenesis, via the deubiquitination of cyclins and Aurora-A. Other tumorigenic molecules, including epidermal growth factor and fatty acid synthase, are also ta...
Main Authors: | Hiroshi Kitamura, Mayuko Hashimoto |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/3/1209 |
Similar Items
-
Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders
by: Hiroshi Kitamura
Published: (2023-02-01) -
Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619
by: Mélanie Lavaud, et al.
Published: (2021-08-01) -
USP37 Deubiquitinates CDC73 in HPT-JT Syndrome
by: Su Yeon Kim, et al.
Published: (2022-06-01) -
USP38 exacerbates atrial inflammation, fibrosis, and susceptibility to atrial fibrillation after myocardial infarction in mice
by: Yang Gong, et al.
Published: (2023-11-01) -
Suppression of USP7 negatively regulates the stability of ETS proto-oncogene 2 protein
by: Hong-Beom Park, et al.
Published: (2023-06-01)