Site-specific identification and quantitation of endogenous SUMO modifications under native conditions

Site-specific identification and quantitation of endogenous SUMO modifications under native conditions

SUMOylation is post-translational modification implicated in several biological pathways. Here the authors describe an approach for the global profiling of SUMO attachment sites under native conditions that also allows the parallel determination of SUMO and Ub attachments.

Bibliographic Details
Main Authors: Ryan J. Lumpkin, Hongbo Gu, Yiying Zhu, Marilyn Leonard, Alla S. Ahmad, Karl R. Clauser, Jesse G. Meyer, Eric J. Bennett, Elizabeth A. Komives
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01271-3
Description
Summary:SUMOylation is post-translational modification implicated in several biological pathways. Here the authors describe an approach for the global profiling of SUMO attachment sites under native conditions that also allows the parallel determination of SUMO and Ub attachments.
ISSN:2041-1723

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