Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats
Goat milk is source of different lipids, including conjugated linoleic acid (CLA). CLA reduces body fat and protect against cardiovascular diseases. In the present study fat from goat milk naturally enriched with CLA was used. Male Wistar rats were divided into three groups that received during a 10...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-03-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/19/3/3820 |
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| author | Raphaela Rodrigues Juliana Soares Hugo Garcia Claudenice Nascimento Maria Medeiros Marco Bomfim Maria Carmo Medeiros Rita Queiroga |
| author_facet | Raphaela Rodrigues Juliana Soares Hugo Garcia Claudenice Nascimento Maria Medeiros Marco Bomfim Maria Carmo Medeiros Rita Queiroga |
| author_sort | Raphaela Rodrigues |
| collection | DOAJ |
| description | Goat milk is source of different lipids, including conjugated linoleic acid (CLA). CLA reduces body fat and protect against cardiovascular diseases. In the present study fat from goat milk naturally enriched with CLA was used. Male Wistar rats were divided into three groups that received during a 10 week diet with different lipid sources: soybean oil (CON), coconut oil (CO) and goat milk fat naturally enriched with CLA (GM-CLA). We evaluated the effects of a GM-CLA on biochemistry parameters - high density lipoprotein (HDL), triacylglycerol (TAG), TAG/HDL ratio, total cholesterol and glucose -, body weight and histopathological aspects of the intestine and liver. GM-CLA increased body weight from the second to the fifth week of the experiment compared to CON. Feed intake differed between the CON group and GM-CLA early in the first to third week of the experiments and later between the ninth and tenth week. The CLA-diet group showed increased levels of HDL, reduced levels of TAG and TAG/HDL ratio and no effect on LDL, but enhanced total cholesterol. Serum glucose of the GM-CLA group showed no difference from the control group. Thus, a GM-CLA diet promoted growth in young rats and acted as protector of cardiovascular function, but further studies are still needed to clarify these effects. |
| first_indexed | 2024-12-19T10:04:48Z |
| format | Article |
| id | doaj.art-f0268a8a126b4f10920bcb8fbb39d1a9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-19T10:04:48Z |
| publishDate | 2014-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f0268a8a126b4f10920bcb8fbb39d1a92022-12-21T20:26:33ZengMDPI AGMolecules1420-30492014-03-011933820383110.3390/molecules19033820molecules19033820Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in RatsRaphaela Rodrigues0Juliana Soares1Hugo Garcia2Claudenice Nascimento3Maria Medeiros4Marco Bomfim5Maria Carmo Medeiros6Rita Queiroga7Departament of Nutrition, Universidade Federal de Campina Grande, Cuité 58175-000, PB, BrazilDepartament of Nutrition, Universidade Federal de Campina Grande, Cuité 58175-000, PB, BrazilDepartament of Morfology, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, BrazilEscola Técnica de Saúde, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, BrazilDepartament of Physiology and Pathology, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, BrazilEmpresa Brasileira de Pesquisa Agropecuária, EMBRAPA Caprinos e Ovinos, Sobral 62010-970, CE, BrazilDepartament of Nutrition, Universidade Federal de Pernambuco, Recife 50670-901, PE, BrazilDepartament of Nutrition, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, BrazilGoat milk is source of different lipids, including conjugated linoleic acid (CLA). CLA reduces body fat and protect against cardiovascular diseases. In the present study fat from goat milk naturally enriched with CLA was used. Male Wistar rats were divided into three groups that received during a 10 week diet with different lipid sources: soybean oil (CON), coconut oil (CO) and goat milk fat naturally enriched with CLA (GM-CLA). We evaluated the effects of a GM-CLA on biochemistry parameters - high density lipoprotein (HDL), triacylglycerol (TAG), TAG/HDL ratio, total cholesterol and glucose -, body weight and histopathological aspects of the intestine and liver. GM-CLA increased body weight from the second to the fifth week of the experiment compared to CON. Feed intake differed between the CON group and GM-CLA early in the first to third week of the experiments and later between the ninth and tenth week. The CLA-diet group showed increased levels of HDL, reduced levels of TAG and TAG/HDL ratio and no effect on LDL, but enhanced total cholesterol. Serum glucose of the GM-CLA group showed no difference from the control group. Thus, a GM-CLA diet promoted growth in young rats and acted as protector of cardiovascular function, but further studies are still needed to clarify these effects.http://www.mdpi.com/1420-3049/19/3/3820lipidsgoat milksteatosischolesterollipoproteinrats |
| spellingShingle | Raphaela Rodrigues Juliana Soares Hugo Garcia Claudenice Nascimento Maria Medeiros Marco Bomfim Maria Carmo Medeiros Rita Queiroga Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats Molecules lipids goat milk steatosis cholesterol lipoprotein rats |
| title | Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats |
| title_full | Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats |
| title_fullStr | Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats |
| title_full_unstemmed | Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats |
| title_short | Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats |
| title_sort | goat milk fat naturally enriched with conjugated linoleic acid increased lipoproteins and reduced triacylglycerol in rats |
| topic | lipids goat milk steatosis cholesterol lipoprotein rats |
| url | http://www.mdpi.com/1420-3049/19/3/3820 |
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