Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents
AbstractIn this work, a series of novel compounds Spartinin C1-C24 were screened, synthesised and evaluated for inhibiting xanthine oxidase thus lowering serum uric acid level. The backbones were derived from the components of coastal marine source Spartina alterniflora and marketed drugs. The top h...
Main Authors: | Yu-Shun Yang, Bin Wang, Junzhong Liu, Qin Li, Qin-Cai Jiao, Pei Qin |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
|
Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/14756366.2022.2163241 |
Similar Items
-
The possible mechanism of hydroxytyrosol on reducing uric acid levels
by: Yin Wan, et al.
Published: (2018-03-01) -
Uric Acid and Hypertension: Prognostic Role and Guide for Treatment
by: Federica Piani, et al.
Published: (2021-01-01) -
Molecular mechanism underlying the ability of caffeic acid to decrease uric acid levels in hyperuricemia rats
by: Yin Wan, et al.
Published: (2019-06-01) -
Research on the Efficacy of Ganpu Vine Tea in Inhibiting Uric Acid Production
by: Zhi-Xu Zhang, et al.
Published: (2023-05-01) -
Impact of Serum Uric Acid Lowering and Contemporary Uric Acid-Lowering Therapies on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis
by: Hangying Ying, et al.
Published: (2021-03-01)