Acoustic change complex findings in mild and moderate sensorineural hearing loss
Abstract Background Auditory electrophysiological tests of the cortex, which are processed in or close to the auditory cortex, are brain reactions to sound. A variation in a continuous stimulus causes the acoustic change complex potential (ACC), which is a wave following the P1-N1-P2 response. Objec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-02-01
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| Series: | The Egyptian Journal of Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43163-024-00582-9 |
| _version_ | 1797276092240756736 |
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| author | Mona Hamdy Amira El Shennawy Noha Hosny Aya Salah Ezz Elregal Hussein Sherif Hamdy |
| author_facet | Mona Hamdy Amira El Shennawy Noha Hosny Aya Salah Ezz Elregal Hussein Sherif Hamdy |
| author_sort | Mona Hamdy |
| collection | DOAJ |
| description | Abstract Background Auditory electrophysiological tests of the cortex, which are processed in or close to the auditory cortex, are brain reactions to sound. A variation in a continuous stimulus causes the acoustic change complex potential (ACC), which is a wave following the P1-N1-P2 response. Objective To measure the amplitude and latency of different components of ACC in normal subjects and across individuals with mild and moderate degrees of sensorineural hearing loss (SNHL). Patients and methods The study includes 100 individuals with the age ranged from 10 to 50 years with different degrees of SNHL. The ACC was evoked by a change of second formant in the middle of ongoing steady-state synthetic, 3 formant vowels (ooee). The total duration was 500 ms. Changing occurred at 250 ms. Results The SNHL subgroups showed statistically significantly longer P1 and N1 latencies. N1 and P2 amplitudes of ACC onset response were larger with a statistical significance as compared to controls. Post hoc analysis revealed no statistically significant difference between mild and moderate SNHL on ACC parameters. Age showed a significant negative correlation with ACC N1 and P2 latency, ACC P1 and N1 amplitude, and onset P2 latency. Onset response P1 latency was significantly higher in children than adults. Median ACC P1 amplitude significantly increased in children than adults. Conclusion ACC is a reliable tool for testing the auditory cortex function of detecting difference in sounds presented that can be recorded readily in patients with mild and moderate SNHL. |
| first_indexed | 2024-03-07T15:23:23Z |
| format | Article |
| id | doaj.art-f0276a5db34f43eeab62dbf2a902b3ac |
| institution | Directory Open Access Journal |
| issn | 2090-8539 |
| language | English |
| last_indexed | 2024-03-07T15:23:23Z |
| publishDate | 2024-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Otolaryngology |
| spelling | doaj.art-f0276a5db34f43eeab62dbf2a902b3ac2024-03-05T17:30:07ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392024-02-0140111110.1186/s43163-024-00582-9Acoustic change complex findings in mild and moderate sensorineural hearing lossMona Hamdy0Amira El Shennawy1Noha Hosny2Aya Salah Ezz Elregal3Hussein Sherif Hamdy4Audiology Unit, Otolaryngology Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityAudiology Unit, Otolaryngology Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityAudiology Unit, Otolaryngology Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityAudiology Unit, Otolaryngology Department, Faculty of Medicine, Benha UniversityAudiology Unit, Otolaryngology Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityAbstract Background Auditory electrophysiological tests of the cortex, which are processed in or close to the auditory cortex, are brain reactions to sound. A variation in a continuous stimulus causes the acoustic change complex potential (ACC), which is a wave following the P1-N1-P2 response. Objective To measure the amplitude and latency of different components of ACC in normal subjects and across individuals with mild and moderate degrees of sensorineural hearing loss (SNHL). Patients and methods The study includes 100 individuals with the age ranged from 10 to 50 years with different degrees of SNHL. The ACC was evoked by a change of second formant in the middle of ongoing steady-state synthetic, 3 formant vowels (ooee). The total duration was 500 ms. Changing occurred at 250 ms. Results The SNHL subgroups showed statistically significantly longer P1 and N1 latencies. N1 and P2 amplitudes of ACC onset response were larger with a statistical significance as compared to controls. Post hoc analysis revealed no statistically significant difference between mild and moderate SNHL on ACC parameters. Age showed a significant negative correlation with ACC N1 and P2 latency, ACC P1 and N1 amplitude, and onset P2 latency. Onset response P1 latency was significantly higher in children than adults. Median ACC P1 amplitude significantly increased in children than adults. Conclusion ACC is a reliable tool for testing the auditory cortex function of detecting difference in sounds presented that can be recorded readily in patients with mild and moderate SNHL.https://doi.org/10.1186/s43163-024-00582-9SensorineuralAcoustic change complexCortical evoked potentialsHearing loss |
| spellingShingle | Mona Hamdy Amira El Shennawy Noha Hosny Aya Salah Ezz Elregal Hussein Sherif Hamdy Acoustic change complex findings in mild and moderate sensorineural hearing loss The Egyptian Journal of Otolaryngology Sensorineural Acoustic change complex Cortical evoked potentials Hearing loss |
| title | Acoustic change complex findings in mild and moderate sensorineural hearing loss |
| title_full | Acoustic change complex findings in mild and moderate sensorineural hearing loss |
| title_fullStr | Acoustic change complex findings in mild and moderate sensorineural hearing loss |
| title_full_unstemmed | Acoustic change complex findings in mild and moderate sensorineural hearing loss |
| title_short | Acoustic change complex findings in mild and moderate sensorineural hearing loss |
| title_sort | acoustic change complex findings in mild and moderate sensorineural hearing loss |
| topic | Sensorineural Acoustic change complex Cortical evoked potentials Hearing loss |
| url | https://doi.org/10.1186/s43163-024-00582-9 |
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