Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study

Background: Diabetes is a stronger risk factor for cardiovascular complications in women than men. Aim: To evaluate whether there are sex differences in cardiovascular risk management in patients with diabetes in primary care. Design & setting: A cross-sectional study was undertaken using data f...

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Main Authors: Marit de Jong, Rimke C Vos, Rianneke de Ritter, Carla J van der Kallen, Simone J Sep, Mark Woodward, Coen DA Stehouwer, Michiel L Bots, Sanne AE Peters
Format: Article
Language:English
Published: Royal College of General Practitioners 2019-01-01
Series:BJGP Open
Subjects:
Online Access:https://bjgpopen.org/content/3/2/bjgpopen19X101645
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author Marit de Jong
Rimke C Vos
Rianneke de Ritter
Carla J van der Kallen
Simone J Sep
Mark Woodward
Coen DA Stehouwer
Michiel L Bots
Sanne AE Peters
author_facet Marit de Jong
Rimke C Vos
Rianneke de Ritter
Carla J van der Kallen
Simone J Sep
Mark Woodward
Coen DA Stehouwer
Michiel L Bots
Sanne AE Peters
author_sort Marit de Jong
collection DOAJ
description Background: Diabetes is a stronger risk factor for cardiovascular complications in women than men. Aim: To evaluate whether there are sex differences in cardiovascular risk management in patients with diabetes in primary care. Design & setting: A cross-sectional study was undertaken using data from 12 512 individuals with diabetes within the Dutch Julius General Practitioners Network (JGPN) from 2013. Method: Linear and Poisson regression analyses were used to assess sex differences in risk factor levels, assessment, treatment, and control. Results: No sex differences were found in HbA1c levels and control, while small differences were found for cardiovascular risk management. Blood pressure levels were higher (mean difference [MD] 1.09 mmHg; 95% confidence intervals [CI] = 0.41 to 1.77), while cholesterol levels (MD -0.38 mmol/l; 95% CI = -0.42 to -0.34) and body mass index ([BMI] MD -1.79 kg/m2; 95% CI = -2.03 to 1.56) were lower in men than women. Risk factor assessment was similar between sexes, apart from high-density lipoprotein cholesterol (HDL-c), which was more commonly assessed in women (risk ratio [RR] 1.16; 95% CI = 1.13 to 1.20). Among those with a treatment indication for prevention, women with cardiovascular disease (CVD) were less likely to receive lipid-lowering drugs (RR 0.84; 95% CI = 0.76 to 0.93) than men, while women without CVD were more likely to receive lipid-lowering drugs (RR 1.16; 95% CI = 1.04 to 1.2). Among those treated, women were more likely to achieve systolic blood pressure (SBP) control (RR 1.06; 95% CI = 1.02 to 1.10) and less likely to achieve low-density lipoprotein cholesterol (LDL-c) control (RR 0.88; 95% CI = 0.85 to 0.91) than men. Conclusion: In this Dutch primary care setting, sex differences in risk factor assessment and treatment of people with diabetes were small. However, women with diabetes were less likely to achieve control for LDL-c and more likely to achieve blood pressure control than men with diabetes.
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spelling doaj.art-f02e110d0bb54f41af73be3e92e46fcb2022-12-21T17:59:57ZengRoyal College of General PractitionersBJGP Open2398-37952019-01-013210.3399/bjgpopen19X101645Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional studyMarit de Jong0Rimke C Vos1Rianneke de Ritter2Carla J van der Kallen3Simone J Sep4Mark Woodward5Coen DA Stehouwer6Michiel L Bots7Sanne AE Peters8Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The NetherlandsDepartment of Public Health and Primary Care / LUMC-Campus, Leiden University Medical Center, The Hague, The NetherlandsDepartment of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The NetherlandsDepartment of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The NetherlandsDepartment of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The NetherlandsThe George Institute for Global Health, University of Oxford, Oxford, UKDepartment of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The NetherlandsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The NetherlandsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The NetherlandsBackground: Diabetes is a stronger risk factor for cardiovascular complications in women than men. Aim: To evaluate whether there are sex differences in cardiovascular risk management in patients with diabetes in primary care. Design & setting: A cross-sectional study was undertaken using data from 12 512 individuals with diabetes within the Dutch Julius General Practitioners Network (JGPN) from 2013. Method: Linear and Poisson regression analyses were used to assess sex differences in risk factor levels, assessment, treatment, and control. Results: No sex differences were found in HbA1c levels and control, while small differences were found for cardiovascular risk management. Blood pressure levels were higher (mean difference [MD] 1.09 mmHg; 95% confidence intervals [CI] = 0.41 to 1.77), while cholesterol levels (MD -0.38 mmol/l; 95% CI = -0.42 to -0.34) and body mass index ([BMI] MD -1.79 kg/m2; 95% CI = -2.03 to 1.56) were lower in men than women. Risk factor assessment was similar between sexes, apart from high-density lipoprotein cholesterol (HDL-c), which was more commonly assessed in women (risk ratio [RR] 1.16; 95% CI = 1.13 to 1.20). Among those with a treatment indication for prevention, women with cardiovascular disease (CVD) were less likely to receive lipid-lowering drugs (RR 0.84; 95% CI = 0.76 to 0.93) than men, while women without CVD were more likely to receive lipid-lowering drugs (RR 1.16; 95% CI = 1.04 to 1.2). Among those treated, women were more likely to achieve systolic blood pressure (SBP) control (RR 1.06; 95% CI = 1.02 to 1.10) and less likely to achieve low-density lipoprotein cholesterol (LDL-c) control (RR 0.88; 95% CI = 0.85 to 0.91) than men. Conclusion: In this Dutch primary care setting, sex differences in risk factor assessment and treatment of people with diabetes were small. However, women with diabetes were less likely to achieve control for LDL-c and more likely to achieve blood pressure control than men with diabetes.https://bjgpopen.org/content/3/2/bjgpopen19X101645primary health caresex characteristicsdiabetes mellituscardiovascular risk managementgeneral practice
spellingShingle Marit de Jong
Rimke C Vos
Rianneke de Ritter
Carla J van der Kallen
Simone J Sep
Mark Woodward
Coen DA Stehouwer
Michiel L Bots
Sanne AE Peters
Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
BJGP Open
primary health care
sex characteristics
diabetes mellitus
cardiovascular risk management
general practice
title Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
title_full Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
title_fullStr Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
title_full_unstemmed Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
title_short Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study
title_sort sex differences in cardiovascular risk management for people with diabetes in primary care a cross sectional study
topic primary health care
sex characteristics
diabetes mellitus
cardiovascular risk management
general practice
url https://bjgpopen.org/content/3/2/bjgpopen19X101645
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