Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes
Until now injectable glucagon was the only available treatment used in the management of severe hypoglycemia wherein glucagon had to be prepared in several steps before administration. This method of delivery of injectable glucagon being cumbersome and unappealing for a wide majority of the patients...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Diabetology |
| Subjects: | |
| Online Access: | http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2021;volume=12;issue=2;spage=114;epage=119;aulast=Heba |
| _version_ | 1818724909500596224 |
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| author | Salva Fatima Heba Uzma Parveen Sara Sana Ayesha Khanum Maaria Gulnaaz Maimuna Tabassum Syeda Batool Safiyya |
| author_facet | Salva Fatima Heba Uzma Parveen Sara Sana Ayesha Khanum Maaria Gulnaaz Maimuna Tabassum Syeda Batool Safiyya |
| author_sort | Salva Fatima Heba |
| collection | DOAJ |
| description | Until now injectable glucagon was the only available treatment used in the management of severe hypoglycemia wherein glucagon had to be prepared in several steps before administration. This method of delivery of injectable glucagon being cumbersome and unappealing for a wide majority of the patients had led to a search for an alternative route of drug delivery. Intranasal (IN) glucagon now serves an efficient, safe, easy to administer, and a favorable substitute to glucagon injections. This ready-to-use device stands in clear contrast to overcome the limitations associated with the currently available glucagon preparations, which has emerged a key advancement in the management of severe hypoglycemia in adolescents and children with type 1 diabetes. IN glucagon is now being developed and studied in other countries as well to meet the unmet need for an easy and convenient glucagon administration. This review covers the basic information of nasal glucagon, trials on nasal glucagon in children’s and adults, and its potential uses, limitations, and future scope in practice. |
| first_indexed | 2024-12-17T21:33:54Z |
| format | Article |
| id | doaj.art-f02f0f8f7769417891e59bc8fe71526e |
| institution | Directory Open Access Journal |
| issn | 2078-7685 |
| language | English |
| last_indexed | 2024-12-17T21:33:54Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Diabetology |
| spelling | doaj.art-f02f0f8f7769417891e59bc8fe71526e2022-12-21T21:31:48ZengWolters Kluwer Medknow PublicationsJournal of Diabetology2078-76852021-01-0112211411910.4103/jod.jod_26_20Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetesSalva Fatima HebaUzma ParveenSara Sana Ayesha KhanumMaaria GulnaazMaimuna TabassumSyeda Batool SafiyyaUntil now injectable glucagon was the only available treatment used in the management of severe hypoglycemia wherein glucagon had to be prepared in several steps before administration. This method of delivery of injectable glucagon being cumbersome and unappealing for a wide majority of the patients had led to a search for an alternative route of drug delivery. Intranasal (IN) glucagon now serves an efficient, safe, easy to administer, and a favorable substitute to glucagon injections. This ready-to-use device stands in clear contrast to overcome the limitations associated with the currently available glucagon preparations, which has emerged a key advancement in the management of severe hypoglycemia in adolescents and children with type 1 diabetes. IN glucagon is now being developed and studied in other countries as well to meet the unmet need for an easy and convenient glucagon administration. This review covers the basic information of nasal glucagon, trials on nasal glucagon in children’s and adults, and its potential uses, limitations, and future scope in practice.http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2021;volume=12;issue=2;spage=114;epage=119;aulast=Hebacumbersomehypoglycemiainjectable glucagonintranasal glucagonmanagement |
| spellingShingle | Salva Fatima Heba Uzma Parveen Sara Sana Ayesha Khanum Maaria Gulnaaz Maimuna Tabassum Syeda Batool Safiyya Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes Journal of Diabetology cumbersome hypoglycemia injectable glucagon intranasal glucagon management |
| title | Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes |
| title_full | Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes |
| title_fullStr | Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes |
| title_full_unstemmed | Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes |
| title_short | Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes |
| title_sort | inhaled glucagon a new hope for severe hypoglycemia in type 1 diabetes |
| topic | cumbersome hypoglycemia injectable glucagon intranasal glucagon management |
| url | http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2021;volume=12;issue=2;spage=114;epage=119;aulast=Heba |
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