Population pharmacokinetic analysis of the P2X3‐receptor antagonist gefapixant

Abstract Gefapixant, a P2X3‐receptor antagonist, demonstrated objective and subjective efficacy in individuals with refractory or unexplained chronic cough. We report a population pharmacokinetic (PopPK) analysis that characterizes gefapixant pharmacokinetics (PKs), quantifies between‐ and within‐pa...

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Bibliographic Details
Main Authors: Akshita Chawla, Anna Largajolli, Azher Hussain, Huub Kleijn, Sihem Ait‐Oudhia, Judith Anton, Hari Krishna Ananthula, Jesse Nussbaum, Carmen La Rosa, Ferdous Gheyas
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12978