Cancer-Associated Fibroblasts in Oral Cancer: A Current Perspective on Function and Potential for Therapeutic Targeting

Cancer-Associated Fibroblasts in Oral Cancer: A Current Perspective on Function and Potential for Therapeutic Targeting

The role of the tumour microenvironement (TME) in cancer progression and resistance to therapies is now widely recognized. The most prominent non-immune cell type in the microenvironment of oral cancer (OSCC) is cancer-associated fibroblasts (CAF). Although CAF are a poorly characterised and heterog...

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Bibliographic Details
Main Authors: Kamila J. Bienkowska, Christopher J. Hanley, Gareth J. Thomas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oral Health
Subjects:
oral cancer
head & neck squamous cell carcinoma
tumour microenvironment
cancer-associated fibroblasts
myofibroblasts
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2021.686337/full

Internet

https://www.frontiersin.org/articles/10.3389/froh.2021.686337/full

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