Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia

Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia

Abstract Background Berberine (BBR), an isoquinoline alkaloid isolated from Rhizoma Coptis, is widely used in the treatment of hyperlipidemia (HLP) in China. At present, the efficacy of BBR against HLP is relatively clear, but there are few researches on its mechanism. The purpose of this study was...

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Bibliographic Details
Main Authors: Yuting Chen, Kaipeng Li, Han Zhao, Zhangsen Hao, Yuxin Yang, Mingming Gao, Ding Zhao
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Translational Medicine
Subjects:
Berberine
Hyperlipidemia
Lipidomics
Network pharmacology
Online Access:https://doi.org/10.1186/s12967-022-03623-0

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