The Role of Pharmaceutical Compounding in Promoting Medication Adherence

Pharmaceutical compounding is an important component of pharmacy practice despite its low prevalence. Several therapeutic needs can be met by a compounded medicine such as dosing adjusted for pediatric patients, special drug combinations, medicines for patients allergic to a given excipient, and med...

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Main Authors: Maria Carvalho, Isabel F. Almeida
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/9/1091
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author Maria Carvalho
Isabel F. Almeida
author_facet Maria Carvalho
Isabel F. Almeida
author_sort Maria Carvalho
collection DOAJ
description Pharmaceutical compounding is an important component of pharmacy practice despite its low prevalence. Several therapeutic needs can be met by a compounded medicine such as dosing adjusted for pediatric patients, special drug combinations, medicines for patients allergic to a given excipient, and medicines for orphan drugs not provided by the pharmaceutical industry. Examples of such applications are provided in this review. Adherence to medication is a critical public health issue as nonadherence to pharmacotherapy has been associated with adverse outcomes and higher costs of patient care. Adherence to therapy represents a key factor in the reduction in morbidity and mortality and optimization of the use of financial resources. The role of pharmaceutical compounding in promoting medication adherence is underexploited. The customization might represent a positive reinforcement of the initiation of the treatment, while implementation and persistence might also be favored in a pharmacy setting. However, studies addressing the influence of compounding in adherence promotion are lacking in the literature. The results of such studies could support health policies including proper regulatory framework, pharmacist training, and information to health care practitioners.
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spelling doaj.art-f03d344a7b5c418e91c1c5e2c52a20e92023-11-23T18:18:27ZengMDPI AGPharmaceuticals1424-82472022-08-01159109110.3390/ph15091091The Role of Pharmaceutical Compounding in Promoting Medication AdherenceMaria Carvalho0Isabel F. Almeida1Professional Compounding Centers of America (PCCA), Department of Research & Development, Houston, TX 77099, USAUCIBIO-REQUIMTE, MedTech, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, PortugalPharmaceutical compounding is an important component of pharmacy practice despite its low prevalence. Several therapeutic needs can be met by a compounded medicine such as dosing adjusted for pediatric patients, special drug combinations, medicines for patients allergic to a given excipient, and medicines for orphan drugs not provided by the pharmaceutical industry. Examples of such applications are provided in this review. Adherence to medication is a critical public health issue as nonadherence to pharmacotherapy has been associated with adverse outcomes and higher costs of patient care. Adherence to therapy represents a key factor in the reduction in morbidity and mortality and optimization of the use of financial resources. The role of pharmaceutical compounding in promoting medication adherence is underexploited. The customization might represent a positive reinforcement of the initiation of the treatment, while implementation and persistence might also be favored in a pharmacy setting. However, studies addressing the influence of compounding in adherence promotion are lacking in the literature. The results of such studies could support health policies including proper regulatory framework, pharmacist training, and information to health care practitioners.https://www.mdpi.com/1424-8247/15/9/1091geriatric formulationsmedication adherencepatient-centric designpediatric formulationspharmaceutical compoundingpharmaceutical intervention
spellingShingle Maria Carvalho
Isabel F. Almeida
The Role of Pharmaceutical Compounding in Promoting Medication Adherence
Pharmaceuticals
geriatric formulations
medication adherence
patient-centric design
pediatric formulations
pharmaceutical compounding
pharmaceutical intervention
title The Role of Pharmaceutical Compounding in Promoting Medication Adherence
title_full The Role of Pharmaceutical Compounding in Promoting Medication Adherence
title_fullStr The Role of Pharmaceutical Compounding in Promoting Medication Adherence
title_full_unstemmed The Role of Pharmaceutical Compounding in Promoting Medication Adherence
title_short The Role of Pharmaceutical Compounding in Promoting Medication Adherence
title_sort role of pharmaceutical compounding in promoting medication adherence
topic geriatric formulations
medication adherence
patient-centric design
pediatric formulations
pharmaceutical compounding
pharmaceutical intervention
url https://www.mdpi.com/1424-8247/15/9/1091
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