Senescent Cells Impair Erectile Function through Induction of Endothelial Dysfunction and Nerve Injury in Mice.
Erectile dysfunction (ED) is a major health problem, particularly in the elderly population, which is rapidly increasing. It is necessary to elucidate the mechanism by which ED occurs in the elderly. Cellular senescence is commonly detected in old tissues, and it is well known that senescent cells n...
Main Authors: | Hiroaki Nishimatsu, Etsu Suzuki, Yasuho Saito, Aya Niimi, Akira Nomiya, Hiroshi Fukuhara, Haruki Kume, Yukio Homma |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4404101?pdf=render |
Similar Items
-
Neuromedin B Restores Erectile Function by Protecting the Cavernous Body and the Nitrergic Nerves from Injury in a Diabetic Rat Model.
by: Hiroaki Nishimatsu, et al.
Published: (2015-01-01) -
Efficacy and Safety of Low-dose Oral Prednisolone for Patients with Refractory Hunner-type Interstitial Cystitis
by: Yoshiyuki Akiyama, et al.
Published: (2023-10-01) -
Robot-assisted radical prostatectomy significantly reduced biochemical recurrence compared to retro pubic radical prostatectomy
by: Tetsuya Fujimura, et al.
Published: (2017-06-01) -
Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats
by: Yinghao Yin, et al.
Published: (2023-01-01) -
Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis
by: Yoshiyuki Akiyama, et al.
Published: (2021-01-01)