Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum
Background: Radiotherapy with large mantle field is an effective technique in increasing the risk of secondary cancers among HL (Hodgkin Lymphoma) patients; therefore, it is essential to choose an effective treatment field including the least medical conditions in radiotherapy. Objective: The pre...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2018-03-01
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| Series: | Journal of Biomedical Physics and Engineering |
| Subjects: | |
| Online Access: | http://www.jbpe.org/Journal_OJS/JBPE/index.php/jbpe/article/view/759 |
| _version_ | 1811259878919897088 |
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| author | Tavakoli M. B. Maleki M. Akhavan A. Hadisinia T. Abedi I. Amouheidari A. |
| author_facet | Tavakoli M. B. Maleki M. Akhavan A. Hadisinia T. Abedi I. Amouheidari A. |
| author_sort | Tavakoli M. B. |
| collection | DOAJ |
| description | Background: Radiotherapy with large mantle field is an effective technique in increasing the risk of secondary cancers among HL (Hodgkin Lymphoma) patients; therefore, it is essential to choose an effective treatment field including the least medical conditions in radiotherapy.
Objective: The present study aimed to plan separate fields for neck and mediastinum using various energies, to compare dose distribution with MLC and to block field formation.
Materials and Methods: In this study, 3D conformal treatments, Siemens Oncor accelerator equipped with multi-leaf collimator (MLC) were performed to create anterior-posterior fields. CT-scan data of 18 female patients with neck and mediastinal involvement was imported in TIGRT treatment planning system, and then treatment plans were introduced.
Results and Conclusion: Using treatment plan 1, photon 6 MV in neck weighting 1 from interior, 0.5 from posterior, photon 18MV in mediastinum weighting 1 from interior and 0.5 from posterior, it was shown that regarding the common treatment plan used with photon 6 MV, mean dose delivered to breast, lung, esophagus and larynx reduced 6, 7, 41 and 10 percent, respectively and uniformity index improved by 10 percent. Using block compared to MLC in all treatment plans offered improved average dose in all organs under study. To protect breast and lung while using MLC and block in the first treatment plan seemed to be more appropriate; however, using blocks in comparison to MLC increased delivered mean dose in all organs under study. Using separate fields with Pb blocks, though, showed smaller increase. |
| first_indexed | 2024-04-12T18:38:16Z |
| format | Article |
| id | doaj.art-f044cd4e20684343864e77babddeeb39 |
| institution | Directory Open Access Journal |
| issn | 2251-7200 2251-7200 |
| language | English |
| last_indexed | 2024-04-12T18:38:16Z |
| publishDate | 2018-03-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Biomedical Physics and Engineering |
| spelling | doaj.art-f044cd4e20684343864e77babddeeb392022-12-22T03:20:52ZengShiraz University of Medical SciencesJournal of Biomedical Physics and Engineering2251-72002251-72002018-03-0181657210.22086/jbpe.v0i0.759Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and MediastinumTavakoli M. B.0Maleki M.1Akhavan A.2Hadisinia T.3Abedi I.4Amouheidari A.5Professor, Department of Medical Physics and Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranM.Sc., Department of Medical Physics and Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssistant Professor, Department of Radiation-Oncology, Isfahan University of Medical Sciences, Isfahan, IranPh.D. Student, Department of Medical Physics and Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, IranPh.D. Student, Department of Medical Physics and Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranOncologist, Department of Radiation Oncology, Isfahan Milad Hospital, Isfahan, IranBackground: Radiotherapy with large mantle field is an effective technique in increasing the risk of secondary cancers among HL (Hodgkin Lymphoma) patients; therefore, it is essential to choose an effective treatment field including the least medical conditions in radiotherapy. Objective: The present study aimed to plan separate fields for neck and mediastinum using various energies, to compare dose distribution with MLC and to block field formation. Materials and Methods: In this study, 3D conformal treatments, Siemens Oncor accelerator equipped with multi-leaf collimator (MLC) were performed to create anterior-posterior fields. CT-scan data of 18 female patients with neck and mediastinal involvement was imported in TIGRT treatment planning system, and then treatment plans were introduced. Results and Conclusion: Using treatment plan 1, photon 6 MV in neck weighting 1 from interior, 0.5 from posterior, photon 18MV in mediastinum weighting 1 from interior and 0.5 from posterior, it was shown that regarding the common treatment plan used with photon 6 MV, mean dose delivered to breast, lung, esophagus and larynx reduced 6, 7, 41 and 10 percent, respectively and uniformity index improved by 10 percent. Using block compared to MLC in all treatment plans offered improved average dose in all organs under study. To protect breast and lung while using MLC and block in the first treatment plan seemed to be more appropriate; however, using blocks in comparison to MLC increased delivered mean dose in all organs under study. Using separate fields with Pb blocks, though, showed smaller increase.http://www.jbpe.org/Journal_OJS/JBPE/index.php/jbpe/article/view/759Treatment PlanningRadiotherapyHodgkinMLC3D Conformal |
| spellingShingle | Tavakoli M. B. Maleki M. Akhavan A. Hadisinia T. Abedi I. Amouheidari A. Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum Journal of Biomedical Physics and Engineering Treatment Planning Radiotherapy Hodgkin MLC 3D Conformal |
| title | Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum |
| title_full | Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum |
| title_fullStr | Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum |
| title_full_unstemmed | Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum |
| title_short | Comparison and Evaluation of Different Treatment Plans with IFRT Field and 6 and 18 MV Energies in Hodgkin’s Lymphoma Involvement Neck and Mediastinum |
| title_sort | comparison and evaluation of different treatment plans with ifrt field and 6 and 18 mv energies in hodgkin s lymphoma involvement neck and mediastinum |
| topic | Treatment Planning Radiotherapy Hodgkin MLC 3D Conformal |
| url | http://www.jbpe.org/Journal_OJS/JBPE/index.php/jbpe/article/view/759 |
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