Early life stress in depressive patients: HPA axis response to GR and MR agonist
Background: Evidence indicates that early life stress (ELS) can induce persistent changes in the HPA axis to respond to stress in the adult life, lead to depression. These appear to be related to the impaired of HPA hormones through binding to glucocorticoid (GR) and mineralocorticoid receptors (MR)...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-01-01
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Series: | Frontiers in Psychiatry |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00002/full |