Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases
To investigate the physiopathology of pain in chronic inflammatory rheumatic diseases (CIRDs), we assessed the prevalence of migraine and neuropathic pain in 499 patients with CIRDs. We studied 238 patients with rheumatoid arthritis, 188 with spondyloarthritis (SpA), 72 with psoriatic arthritis (PsA...
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MDPI AG
2020-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/6/1890 |
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| author | Sylvain Mathieu Marion Couderc Bruno Pereira Jean-Jacques Dubost Sandrine Malochet-Guinamand Anne Tournadre Martin Soubrier Xavier Moisset |
| author_facet | Sylvain Mathieu Marion Couderc Bruno Pereira Jean-Jacques Dubost Sandrine Malochet-Guinamand Anne Tournadre Martin Soubrier Xavier Moisset |
| author_sort | Sylvain Mathieu |
| collection | DOAJ |
| description | To investigate the physiopathology of pain in chronic inflammatory rheumatic diseases (CIRDs), we assessed the prevalence of migraine and neuropathic pain in 499 patients with CIRDs. We studied 238 patients with rheumatoid arthritis, 188 with spondyloarthritis (SpA), 72 with psoriatic arthritis (PsA), and 1 unclassified. Migraine was diagnosed according to IHS migraine diagnostic criteria. Neuropathic pain was diagnosed when patients scored at least 3 on the DN4 questionnaire. Participants completed a validated self-assessment questionnaire. Migraine prevalence was 34% (165/484), and it was highest in PsA. Risk factors for migraine were a high level of anxiety, female sex, young age, and TNF-alpha inhibitor treatment (OR = 1.90 (1.13–3.25)). Besides, high disease activity was a risk factor in SpA. Blood CRP level was not significantly associated with migraine. Of 493 patients with CIRDs, 21.5% had chronic pain with neuropathic characteristics. Compared to the French general population, these patients had significantly higher prevalences of migraine (two-fold) and neuropathic pain (three-fold). This study showed that migraine and neuropathic pain frequently occurred in patients with rheumatic diseases. Therefore, upon reporting residual pain, these patients should be checked for the presence of migraine or neuropathic pain, despite adequate clinical control of rheumatic disease. |
| first_indexed | 2024-03-10T19:07:33Z |
| format | Article |
| id | doaj.art-f0478c3bd4d249cc8373999bda07ec62 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T19:07:33Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-f0478c3bd4d249cc8373999bda07ec622023-11-20T04:04:24ZengMDPI AGJournal of Clinical Medicine2077-03832020-06-0196189010.3390/jcm9061890Prevalence of Migraine and Neuropathic Pain in Rheumatic DiseasesSylvain Mathieu0Marion Couderc1Bruno Pereira2Jean-Jacques Dubost3Sandrine Malochet-Guinamand4Anne Tournadre5Martin Soubrier6Xavier Moisset7Service de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceUnité de biostatistiques (DRCI), CHU Clermont-Ferrand, 63000 Clermont-Ferrand, FranceService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, FranceNeurology Department, Université Clermont Auvergne, CHU de Clermont-Ferrand, Inserm, Neuro-Dol, F-63000 Clermont Ferrand, FranceTo investigate the physiopathology of pain in chronic inflammatory rheumatic diseases (CIRDs), we assessed the prevalence of migraine and neuropathic pain in 499 patients with CIRDs. We studied 238 patients with rheumatoid arthritis, 188 with spondyloarthritis (SpA), 72 with psoriatic arthritis (PsA), and 1 unclassified. Migraine was diagnosed according to IHS migraine diagnostic criteria. Neuropathic pain was diagnosed when patients scored at least 3 on the DN4 questionnaire. Participants completed a validated self-assessment questionnaire. Migraine prevalence was 34% (165/484), and it was highest in PsA. Risk factors for migraine were a high level of anxiety, female sex, young age, and TNF-alpha inhibitor treatment (OR = 1.90 (1.13–3.25)). Besides, high disease activity was a risk factor in SpA. Blood CRP level was not significantly associated with migraine. Of 493 patients with CIRDs, 21.5% had chronic pain with neuropathic characteristics. Compared to the French general population, these patients had significantly higher prevalences of migraine (two-fold) and neuropathic pain (three-fold). This study showed that migraine and neuropathic pain frequently occurred in patients with rheumatic diseases. Therefore, upon reporting residual pain, these patients should be checked for the presence of migraine or neuropathic pain, despite adequate clinical control of rheumatic disease.https://www.mdpi.com/2077-0383/9/6/1890rheumatic diseasesmigraineneuropathic pain |
| spellingShingle | Sylvain Mathieu Marion Couderc Bruno Pereira Jean-Jacques Dubost Sandrine Malochet-Guinamand Anne Tournadre Martin Soubrier Xavier Moisset Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases Journal of Clinical Medicine rheumatic diseases migraine neuropathic pain |
| title | Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases |
| title_full | Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases |
| title_fullStr | Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases |
| title_full_unstemmed | Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases |
| title_short | Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases |
| title_sort | prevalence of migraine and neuropathic pain in rheumatic diseases |
| topic | rheumatic diseases migraine neuropathic pain |
| url | https://www.mdpi.com/2077-0383/9/6/1890 |
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