HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells

HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells

Highlights M6A-related genes with prognosis, PD-L1 and TIME in NSCLC were first assessed. HNRNPC was the most influential m6A regulator predicted prognosis and immunotherapy response. HNRNPC predicted poor prognosis and correlated with tumor invasion and lymph node metastasis. HNRNPC promoted prolif...

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Bibliographic Details
Main Authors: Zhuoyu Gu, Yang Yang, Qian Ma, Hui Wang, Song Zhao, Yu Qi, Yixin Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Respiratory Research
Subjects:
NSCLC
m6A methylation
HNRNPC
Proliferation
Invasion
Online Access:https://doi.org/10.1186/s12931-022-02227-y

Internet

https://doi.org/10.1186/s12931-022-02227-y

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