A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

Biological timers synchronize patterning processes during embryonic development. In the Drosophila embryo, neural progenitors (neuroblasts; NBs) produce a sequence of unique neurons whose identities depend on the sequential expression of temporal transcription factors (TTFs). The stereotypy and prec...

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Bibliographic Details
Main Authors: Inna Averbukh, Sen-Lin Lai, Chris Q Doe, Naama Barkai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
neuroblast
biological timer
robustness
Online Access:https://elifesciences.org/articles/38631

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