The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging
Optical techniques based on diffuse optics have been around for decades now and are making their way into the day-to-day medical applications. Even though the physics foundations of these techniques have been known for many years, practical implementation of these technique were hindered by technolo...
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MDPI AG
2021-05-01
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Online Access: | https://www.mdpi.com/2076-3417/11/10/4616 |
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author | Frédéric Lange Luca Giannoni Ilias Tachtsidis |
author_facet | Frédéric Lange Luca Giannoni Ilias Tachtsidis |
author_sort | Frédéric Lange |
collection | DOAJ |
description | Optical techniques based on diffuse optics have been around for decades now and are making their way into the day-to-day medical applications. Even though the physics foundations of these techniques have been known for many years, practical implementation of these technique were hindered by technological limitations, mainly from the light sources and/or detection electronics. In the past 20 years, the developments of supercontinuum laser (SCL) enabled to unlock some of these limitations, enabling the development of system and methodologies relevant for medical use, notably in terms of spectral monitoring. In this review, we focus on the use of SCL in biomedical diffuse optics, from instrumentation and methods developments to their use for medical applications. A total of 95 publications were identified, from 1993 to 2021. We discuss the advantages of the SCL to cover a large spectral bandwidth with a high spectral power and fast switching against the disadvantages of cost, bulkiness, and long warm up times. Finally, we summarize the utility of using such light sources in the development and application of diffuse optics in biomedical sciences and clinical applications. |
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issn | 2076-3417 |
language | English |
last_indexed | 2024-03-10T11:18:35Z |
publishDate | 2021-05-01 |
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series | Applied Sciences |
spelling | doaj.art-f0554821a4d14781a2ed0d2f2460ae752023-11-21T20:17:26ZengMDPI AGApplied Sciences2076-34172021-05-011110461610.3390/app11104616The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral ImagingFrédéric Lange0Luca Giannoni1Ilias Tachtsidis2Biomedical Optics Research Laboratory, Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UKBiomedical Optics Research Laboratory, Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UKBiomedical Optics Research Laboratory, Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UKOptical techniques based on diffuse optics have been around for decades now and are making their way into the day-to-day medical applications. Even though the physics foundations of these techniques have been known for many years, practical implementation of these technique were hindered by technological limitations, mainly from the light sources and/or detection electronics. In the past 20 years, the developments of supercontinuum laser (SCL) enabled to unlock some of these limitations, enabling the development of system and methodologies relevant for medical use, notably in terms of spectral monitoring. In this review, we focus on the use of SCL in biomedical diffuse optics, from instrumentation and methods developments to their use for medical applications. A total of 95 publications were identified, from 1993 to 2021. We discuss the advantages of the SCL to cover a large spectral bandwidth with a high spectral power and fast switching against the disadvantages of cost, bulkiness, and long warm up times. Finally, we summarize the utility of using such light sources in the development and application of diffuse optics in biomedical sciences and clinical applications.https://www.mdpi.com/2076-3417/11/10/4616supercontinuum laserNIRStissue opticsdiffuse optics |
spellingShingle | Frédéric Lange Luca Giannoni Ilias Tachtsidis The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging Applied Sciences supercontinuum laser NIRS tissue optics diffuse optics |
title | The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging |
title_full | The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging |
title_fullStr | The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging |
title_full_unstemmed | The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging |
title_short | The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging |
title_sort | use of supercontinuum laser sources in biomedical diffuse optics unlocking the power of multispectral imaging |
topic | supercontinuum laser NIRS tissue optics diffuse optics |
url | https://www.mdpi.com/2076-3417/11/10/4616 |
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