Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India

Background: Coronary artery disease has higher prevalence in India than the West. Studies suggest that vascular age of Asian Indians is older to their chronological age, making them more susceptible for the disease. Association between various factors involved in patients having coronary artery dise...

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Main Author: R M Prashanth
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Indian College of Cardiology
Subjects:
Online Access:http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=62;epage=65;aulast=Prashanth
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author_facet R M Prashanth
author_sort R M Prashanth
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description Background: Coronary artery disease has higher prevalence in India than the West. Studies suggest that vascular age of Asian Indians is older to their chronological age, making them more susceptible for the disease. Association between various factors involved in patients having coronary artery disease and their lipid profiles in rural India is not clear. Objectives: The study focuses on the prevalence and comparative analysis of dyslipidemia in the patient group with respect to demographic data and comorbid conditions. Patients and Methods: This was a retrospective study which analysed 957 patients' hospital record in whom angiography was done for their coronary artery disease in a rural south India. Results: Statistically significant data (P < 0.005) were found in case of total cholesterol levels, with a mean being elevated in age below 45 years (178 ± 46 mg/dl) as compared to age above 45 years (167 ± 48 mg/dl). The mean total cholesterol levels were greater (177 ± 49 mg/dl) in women as compared to men (166 ± 48 mg/dl) with P < 0.005. Hypertensive patients showed elevated levels of total cholesterol and triglycerides. Patients with diabetes had elevated triglyceride levels in general. Conclusion: Triglyceride levels might be playing an important role than total cholesterol in the pathophysiology of CAD and for atherogenesis, it is the presence of hypertension with a deranged lipid profile, more so with total cholesterol and triglycerides.
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spelling doaj.art-f05ab950c71c448ca708ad1f17acb6a32024-02-07T12:55:24ZengWolters Kluwer Medknow PublicationsJournal of Indian College of Cardiology1561-88112213-36152021-01-01112626510.4103/JICC.JICC_56_20Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South IndiaR M PrashanthBackground: Coronary artery disease has higher prevalence in India than the West. Studies suggest that vascular age of Asian Indians is older to their chronological age, making them more susceptible for the disease. Association between various factors involved in patients having coronary artery disease and their lipid profiles in rural India is not clear. Objectives: The study focuses on the prevalence and comparative analysis of dyslipidemia in the patient group with respect to demographic data and comorbid conditions. Patients and Methods: This was a retrospective study which analysed 957 patients' hospital record in whom angiography was done for their coronary artery disease in a rural south India. Results: Statistically significant data (P < 0.005) were found in case of total cholesterol levels, with a mean being elevated in age below 45 years (178 ± 46 mg/dl) as compared to age above 45 years (167 ± 48 mg/dl). The mean total cholesterol levels were greater (177 ± 49 mg/dl) in women as compared to men (166 ± 48 mg/dl) with P < 0.005. Hypertensive patients showed elevated levels of total cholesterol and triglycerides. Patients with diabetes had elevated triglyceride levels in general. Conclusion: Triglyceride levels might be playing an important role than total cholesterol in the pathophysiology of CAD and for atherogenesis, it is the presence of hypertension with a deranged lipid profile, more so with total cholesterol and triglycerides.http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=62;epage=65;aulast=Prashanthcoronary artery diseasedyslipidemiavascular age
spellingShingle R M Prashanth
Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
Journal of Indian College of Cardiology
coronary artery disease
dyslipidemia
vascular age
title Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
title_full Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
title_fullStr Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
title_full_unstemmed Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
title_short Finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography: A retrospective study in rural South India
title_sort finding association between lipid profile and demographic and disease status of patients undergoing coronary angiography a retrospective study in rural south india
topic coronary artery disease
dyslipidemia
vascular age
url http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=62;epage=65;aulast=Prashanth
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