Data Mining of Molecular Simulations Suggest Key Amino Acid Residues for Aggregation, Signaling and Drug Action

Alzheimer’s disease, the most common form of dementia, currently has no cure. There are only temporary treatments that reduce symptoms and the progression of the disease. Alzheimer’s disease is characterized by the prevalence of plaques of aggregated amyloid β (Aβ) peptide. Recent treatments to prev...

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Bibliographic Details
Main Authors: Vaibhav Gurunathan, John Hamre, Dmitri K. Klimov, Mohsin Saleet Jafri
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/10/1541