Vitamin C deficiency induces hypoglycemia and cognitive disorder through S-nitrosylation-mediated activation of glycogen synthase kinase 3β

Vitamin C deficiency induces hypoglycemia and cognitive disorder through S-nitrosylation-mediated activation of glycogen synthase kinase 3β

Vitamin C (VC, l-ascorbic acid) is an essential nutrient that plays a key role in metabolism and functions as a potent antioxidant in regulating the S-nitrosylation and denitrosylation of target proteins. The precise function of VC deprivation in glucose homeostasis is still unknown. In the absence...

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Bibliographic Details
Main Authors: Yingying Shu, Chaochun Zou, Yuqing Cai, Qiangqiang He, Xiaowei Wu, Haibin Zhu, Meiyu Qv, Yunqi Chao, Chengyun Xu, Lanfang Tang, Ximei Wu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
VC
GSK3β
S-nitrosylation
Hypoglycemia
Cognitive disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001926

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