Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences

Chronic constipation is a common gastrointestinal disorder, and its management often requires long-term use of laxatives. This review addresses the differences between two commonly used laxatives, lactulose and bisacodyl. The efficacy, side effect profiles, tolerance development, use in special popu...

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Main Authors: Mustafa Reşat Dabak, Kerim Güler
Format: Article
Language:English
Published: Galenos Yayinevi 2023-12-01
Series:Bagcilar Medical Bulletin
Subjects:
Online Access: http://behmedicalbulletin.org/archives/archive-detail/article-preview/comparative-evaluation-of-lactulose-and-bisacodyl-/63452
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author Mustafa Reşat Dabak
Kerim Güler
author_facet Mustafa Reşat Dabak
Kerim Güler
author_sort Mustafa Reşat Dabak
collection DOAJ
description Chronic constipation is a common gastrointestinal disorder, and its management often requires long-term use of laxatives. This review addresses the differences between two commonly used laxatives, lactulose and bisacodyl. The efficacy, side effect profiles, tolerance development, use in special populations, drug interactions, contraindications, and impacts on patient compliance and quality of life of these two laxatives are compared. Both lactulose and bisacodyl are effective in improving bowel movements and are widely used in clinical practice. However, lactulose might present a more favorable profile for certain patient populations when considering factors such as side effect profile, patient compliance, quality of life, and cost-effectiveness. Primary care physicians should consider these aspects when choosing the most appropriate treatment option for their patients, always considering individual patient characteristics and preferences.
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spelling doaj.art-f05d62dfbc654b6c934e1675ac9f53be2023-12-19T10:59:55ZengGalenos YayineviBagcilar Medical Bulletin2547-94312023-12-018433534010.4274/BMB.galenos.2023.2023-08-07313049054Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient PreferencesMustafa Reşat Dabak0Kerim Güler1 University of Health Sciences Turkey, İstanbul Haseki Training and Research Hospital, Clinic of Family Medicine, İstanbul, Turkey İstanbul University, İstanbul Faculty of Medicine, Department of Internal Medicine, İstanbul, Turkey Chronic constipation is a common gastrointestinal disorder, and its management often requires long-term use of laxatives. This review addresses the differences between two commonly used laxatives, lactulose and bisacodyl. The efficacy, side effect profiles, tolerance development, use in special populations, drug interactions, contraindications, and impacts on patient compliance and quality of life of these two laxatives are compared. Both lactulose and bisacodyl are effective in improving bowel movements and are widely used in clinical practice. However, lactulose might present a more favorable profile for certain patient populations when considering factors such as side effect profile, patient compliance, quality of life, and cost-effectiveness. Primary care physicians should consider these aspects when choosing the most appropriate treatment option for their patients, always considering individual patient characteristics and preferences. http://behmedicalbulletin.org/archives/archive-detail/article-preview/comparative-evaluation-of-lactulose-and-bisacodyl-/63452 bisacodylconstipationlactuloselaxativeosmoticpurgativestimulant
spellingShingle Mustafa Reşat Dabak
Kerim Güler
Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
Bagcilar Medical Bulletin
bisacodyl
constipation
lactulose
laxative
osmotic
purgative
stimulant
title Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
title_full Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
title_fullStr Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
title_full_unstemmed Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
title_short Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
title_sort comparative evaluation of lactulose and bisacodyl in the management of chronic constipation efficacy safety and patient preferences
topic bisacodyl
constipation
lactulose
laxative
osmotic
purgative
stimulant
url http://behmedicalbulletin.org/archives/archive-detail/article-preview/comparative-evaluation-of-lactulose-and-bisacodyl-/63452
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