H3.3 kinetics predicts chromatin compaction status of parental genomes in early embryos

H3.3 kinetics predicts chromatin compaction status of parental genomes in early embryos

Abstract Background After fertilization, the fusion of gametes results in the formation of totipotent zygote. During sperm-egg fusion, maternal factors participate in parental chromatin remodeling. H3.3 is a histone H3 variant that plays essential roles in mouse embryogenesis. Methods Here, we used...

Full description

Bibliographic Details
Main Authors: Shi-meng Guo, Xing-ping Liu, Li-quan Zhou
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Reproductive Biology and Endocrinology
Subjects:
H3.3
Chromatin mobility
Totipotency
Online Access:https://doi.org/10.1186/s12958-021-00776-3

Similar Items

Similar Items