Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages.

Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages.

Hemorrhagic meningitis is a fatal complication of anthrax, but its pathogenesis remains poorly understood. The present study examined the role of B. anthracis-secreted metalloprotease InhA on monolayer integrity and permeability of human brain microvasculature endothelial cells (HBMECs) which consti...

Full description

Bibliographic Details
Main Authors: Dhritiman V Mukherjee, Jessica H Tonry, Kwang Sik Kim, Nalini Ramarao, Taissia G Popova, Charles Bailey, Serguei Popov, Myung-Chul Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060093?pdf=render

Similar Items

Similar Items