The Lon protease is essential for full virulence in Pseudomonas aeruginosa.
Pseudomonas aeruginosa PAO1 lon mutants are supersusceptible to ciprofloxacin, and exhibit a defect in cell division and in virulence-related properties, such as swarming, twitching and biofilm formation, despite the fact that the Lon protease is not a traditional regulator. Here we set out to inves...
Main Authors: | Elena B M Breidenstein, Laure Janot, Janine Strehmel, Lucia Fernandez, Patrick K Taylor, Irena Kukavica-Ibrulj, Shaan L Gellatly, Roger C Levesque, Joerg Overhage, Robert E W Hancock |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3492299?pdf=render |
Similar Items
-
Novel roles for two-component regulatory systems in cytotoxicity and virulence-related properties in <em>Pseudomonas aeruginosa</em>
by: Shaan L. Gellatly, et al.
Published: (2018-03-01) -
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa
by: Fernández, Lucía, et al.
Published: (2017) -
A multi-host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58 lacking full virulence
by: Cynthia Gagné-Thivierge, et al.
Published: (2018-03-01) -
Synergy between Human Peptide LL-37 and Polymyxin B against Planktonic and Biofilm Cells of <i>Escherichia coli</i> and <i>Pseudomonas aeruginosa</i>
by: Kylen E. Ridyard, et al.
Published: (2023-02-01) -
The Oxidative Stress Agent Hypochlorite Stimulates c-di-GMP Synthesis and Biofilm Formation in Pseudomonas aeruginosa
by: Nikola Strempel, et al.
Published: (2017-11-01)