Managing ulcerative colitis after surgery

Management of ulcerative colitis after surgery suggested by guidelines (total proctocolectomy with ileal-pouch anal anastomosis) is a big challenge for physicians because patients who believed that their disease had been cured started experiencing very uncomfortable symptoms repeatedly. A high numbe...

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Main Authors: Cristina Calvino-Suarez, Rocío Ferreiro-Iglesias, Iria Baston Rey, Manuel Barreiro-de Acosta
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1081940/full
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author Cristina Calvino-Suarez
Rocío Ferreiro-Iglesias
Iria Baston Rey
Manuel Barreiro-de Acosta
author_facet Cristina Calvino-Suarez
Rocío Ferreiro-Iglesias
Iria Baston Rey
Manuel Barreiro-de Acosta
author_sort Cristina Calvino-Suarez
collection DOAJ
description Management of ulcerative colitis after surgery suggested by guidelines (total proctocolectomy with ileal-pouch anal anastomosis) is a big challenge for physicians because patients who believed that their disease had been cured started experiencing very uncomfortable symptoms repeatedly. A high number of patients develop episodes of pouchitis, which is a non-specific inflammation of the pouch whose etiology is unknown. Antibiotics are the elective treatment for acute pouchitis, but regarding chronic pouchitis, this condition is very complicated to treat due to the absence of well-designed specific studies for this group of patients. Antibiotics, budesonide, and biological therapies are some of the recommended drugs for these patients, but despite their use, some need a permanent ileostomy.
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spelling doaj.art-f0699d6722ca44ccab60ac2dcbab0c0a2023-01-04T18:45:32ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-01910.3389/fmed.2022.10819401081940Managing ulcerative colitis after surgeryCristina Calvino-SuarezRocío Ferreiro-IglesiasIria Baston ReyManuel Barreiro-de AcostaManagement of ulcerative colitis after surgery suggested by guidelines (total proctocolectomy with ileal-pouch anal anastomosis) is a big challenge for physicians because patients who believed that their disease had been cured started experiencing very uncomfortable symptoms repeatedly. A high number of patients develop episodes of pouchitis, which is a non-specific inflammation of the pouch whose etiology is unknown. Antibiotics are the elective treatment for acute pouchitis, but regarding chronic pouchitis, this condition is very complicated to treat due to the absence of well-designed specific studies for this group of patients. Antibiotics, budesonide, and biological therapies are some of the recommended drugs for these patients, but despite their use, some need a permanent ileostomy.https://www.frontiersin.org/articles/10.3389/fmed.2022.1081940/fullpouchitisulcerative colitiscolectomyantibioticsbiologic therapy
spellingShingle Cristina Calvino-Suarez
Rocío Ferreiro-Iglesias
Iria Baston Rey
Manuel Barreiro-de Acosta
Managing ulcerative colitis after surgery
Frontiers in Medicine
pouchitis
ulcerative colitis
colectomy
antibiotics
biologic therapy
title Managing ulcerative colitis after surgery
title_full Managing ulcerative colitis after surgery
title_fullStr Managing ulcerative colitis after surgery
title_full_unstemmed Managing ulcerative colitis after surgery
title_short Managing ulcerative colitis after surgery
title_sort managing ulcerative colitis after surgery
topic pouchitis
ulcerative colitis
colectomy
antibiotics
biologic therapy
url https://www.frontiersin.org/articles/10.3389/fmed.2022.1081940/full
work_keys_str_mv AT cristinacalvinosuarez managingulcerativecolitisaftersurgery
AT rocioferreiroiglesias managingulcerativecolitisaftersurgery
AT iriabastonrey managingulcerativecolitisaftersurgery
AT manuelbarreirodeacosta managingulcerativecolitisaftersurgery