Long-term effects of asthma medication on asthma symptoms: an application of the targeted maximum likelihood estimation

Long-term effects of asthma medication on asthma symptoms: an application of the targeted maximum likelihood estimation

Abstract Background Long-term effectiveness of asthma control medication has been shown in clinical trials but results from observational studies with children and adolescents are lacking. Marginal structural models estimated using targeted maximum likelihood methods are a novel statistiscal approac...

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Bibliographic Details
Main Authors:	Carolin Veit, Ronald Herrera, Gudrun Weinmayr, Jon Genuneit, Doris Windstetter, Christian Vogelberg, Erika von Mutius, Dennis Nowak, Katja Radon, Jessica Gerlich, Tobias Weinmann
Format:	Article
Language:	English
Published:	BMC 2020-12-01
Series:	BMC Medical Research Methodology
Subjects:	Adolescents Asthma Children Control medication Marginal structural models Targeted-maximum likelihood estimation
Online Access:	https://doi.org/10.1186/s12874-020-01175-9

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