Interferon Lambda in the Pathogenesis of Inflammatory Bowel Diseases
Interferon λ (IFN-λ) is critical for host viral defense at mucosal surfaces and stimulates immunomodulatory signals, acting on epithelial cells and few other cell types due to restricted IFN-λ receptor expression. Epithelial cells of the intestine play a critical role in the pathogenesis of Inflamma...
Main Authors: | Jonathan W. Wallace, David A. Constant, Timothy J. Nice |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.767505/full |
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