An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3

An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3

The pregnane X receptor (PXR) is a nuclear receptor (NR) that primarily activates genes involved in drug metabolism. However, PXR also suppresses inflammation. This study investigated the anti-inflammatory activity of PXR1 and the minor isoform PXR3. Luciferase reporter experiments showed that like...

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Bibliographic Details
Main Author:	Jerusalem Alleyne
Format:	Article
Language:	English
Published:	SAGE Publishing 2019-05-01
Series:	European Journal of Inflammation
Online Access:	https://doi.org/10.1177/2058739219848571

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