Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital
Objective:Toxoplasma gondii (T. gondii) is an obligate intracellular parasite. It is regarded as an important cause of morbidity and mortality in congenital contamination and immunosuppressive patients. This study aimed to determine the seropositivity of T. gondii in various ages and patient groups,...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2022-03-01
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| Series: | Türkiye Parazitoloji Dergisi |
| Subjects: | |
| Online Access: |
http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/seroprevalence-of-itoxoplasma-gondii-i-in-differen/50981
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| _version_ | 1797910204727164928 |
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| author | Fatma Esenkaya Taşbent Duygu Beder Mehmet Özdemir Metin Doğan Bahadır Feyzioğlu |
| author_facet | Fatma Esenkaya Taşbent Duygu Beder Mehmet Özdemir Metin Doğan Bahadır Feyzioğlu |
| author_sort | Fatma Esenkaya Taşbent |
| collection | DOAJ |
| description | Objective:Toxoplasma gondii (T. gondii) is an obligate intracellular parasite. It is regarded as an important cause of morbidity and mortality in congenital contamination and immunosuppressive patients. This study aimed to determine the seropositivity of T. gondii in various ages and patient groups, as well as to reveal the current immune status, especially in risk groups.Methods:Results of T. gondii serology conducted between 2015 and 2019 in the medical microbiology laboratory in a university hospital were retrospectively analyzed. In the study, anti-T. gondii IgM, anti-T. gondii IgG antibodies, and anti-T. gondii IgG avidity test results were investigated by the enzyme-linked fluorescent assay method. Additionally, seropositivity rates among immunosuppressed patients and pregnant women, which are risk groups for toxoplasmosis, were revealed. In the identification of the immunosuppressed patients, groups with significant immunosuppression were retrospectively determined by examining their files.Results:The serology of T. gondii was investigated in serum samples of a total of 20.875 individuals, among which 6.220 (29.8%) are males and 14.655 (70.2%) are females. Anti-T. gondii IgM and IgG positivity rates were significantly higher in women than in men. When all years are evaluated, IgM positivity in 16.448 patients and IgG positivity in 4.427 patients were investigated. In the 5-year period, T. gondii IgM seropositivity and T. gondii IgG seropositivity was among all the patients was 2.4% and 24.1%, respectively. While the rate of T. gondii IgG seropositivity in women of childbearing age was 36.1%, it was 42.4% in pregnant women and 14.6% in immunosuppressed patients.Conclusion:T. gondii serology follow-up of pregnant women and immunosuppressed patients in terms of reactivity of latent infection should be advised and toxoplasmosis should be considered in suspicious clinical cases. |
| first_indexed | 2024-04-10T11:20:36Z |
| format | Article |
| id | doaj.art-f072762e2ef7468b8958f0c7a515d985 |
| institution | Directory Open Access Journal |
| issn | 1300-6320 2146-3077 |
| language | English |
| last_indexed | 2024-04-10T11:20:36Z |
| publishDate | 2022-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türkiye Parazitoloji Dergisi |
| spelling | doaj.art-f072762e2ef7468b8958f0c7a515d9852023-02-15T16:18:39ZengGalenos YayineviTürkiye Parazitoloji Dergisi1300-63202146-30772022-03-014611610.4274/tpd.galenos.2021.2573313049054Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our HospitalFatma Esenkaya Taşbent0Duygu Beder1Mehmet Özdemir2Metin Doğan3Bahadır Feyzioğlu4 Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye Objective:Toxoplasma gondii (T. gondii) is an obligate intracellular parasite. It is regarded as an important cause of morbidity and mortality in congenital contamination and immunosuppressive patients. This study aimed to determine the seropositivity of T. gondii in various ages and patient groups, as well as to reveal the current immune status, especially in risk groups.Methods:Results of T. gondii serology conducted between 2015 and 2019 in the medical microbiology laboratory in a university hospital were retrospectively analyzed. In the study, anti-T. gondii IgM, anti-T. gondii IgG antibodies, and anti-T. gondii IgG avidity test results were investigated by the enzyme-linked fluorescent assay method. Additionally, seropositivity rates among immunosuppressed patients and pregnant women, which are risk groups for toxoplasmosis, were revealed. In the identification of the immunosuppressed patients, groups with significant immunosuppression were retrospectively determined by examining their files.Results:The serology of T. gondii was investigated in serum samples of a total of 20.875 individuals, among which 6.220 (29.8%) are males and 14.655 (70.2%) are females. Anti-T. gondii IgM and IgG positivity rates were significantly higher in women than in men. When all years are evaluated, IgM positivity in 16.448 patients and IgG positivity in 4.427 patients were investigated. In the 5-year period, T. gondii IgM seropositivity and T. gondii IgG seropositivity was among all the patients was 2.4% and 24.1%, respectively. While the rate of T. gondii IgG seropositivity in women of childbearing age was 36.1%, it was 42.4% in pregnant women and 14.6% in immunosuppressed patients.Conclusion:T. gondii serology follow-up of pregnant women and immunosuppressed patients in terms of reactivity of latent infection should be advised and toxoplasmosis should be considered in suspicious clinical cases. http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/seroprevalence-of-itoxoplasma-gondii-i-in-differen/50981 toxoplasma gondiielfaimmunosuppressive patientpregnant |
| spellingShingle | Fatma Esenkaya Taşbent Duygu Beder Mehmet Özdemir Metin Doğan Bahadır Feyzioğlu Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital Türkiye Parazitoloji Dergisi toxoplasma gondii elfa immunosuppressive patient pregnant |
| title | Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital |
| title_full | Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital |
| title_fullStr | Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital |
| title_full_unstemmed | Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital |
| title_short | Seroprevalence of Toxoplasma gondii in Different Patient Groups in Our Hospital |
| title_sort | seroprevalence of toxoplasma gondii in different patient groups in our hospital |
| topic | toxoplasma gondii elfa immunosuppressive patient pregnant |
| url |
http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/seroprevalence-of-itoxoplasma-gondii-i-in-differen/50981
|
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