Age-Associated Dysregulation of Integrin Function in Vascular Smooth Muscle

Age-Associated Dysregulation of Integrin Function in Vascular Smooth Muscle

Arterial aging results in a progressive reduction in elasticity of the vessel wall and an impaired ability of aged blood vessels to control local blood flow and pressure. Recently, a new concept has emerged that the stiffness and decreased contractility of vascular smooth muscle (VSM) cells are impo...

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Bibliographic Details
Main Authors: Krishna Raj Ojha, Song Yi Shin, Samuel Padgham, Frida Leon Olmedo, Bohong Guo, Gang Han, Christopher Woodman, Andreea Trache
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Physiology
Subjects:
aging
integrins
actin
vascular smooth muscle
atomic force microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.913673/full

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