Recent advances in microfluidic technology of arterial thrombosis investigations
AbstractMicrofluidic technology has emerged as a powerful tool in studying arterial thrombosis, allowing researchers to construct artificial blood vessels and replicate the hemodynamics of blood flow. This technology has led to significant advancements in understanding thrombosis and platelet adhesi...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Platelets |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/09537104.2024.2316743 |
| _version_ | 1797299393155563520 |
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| author | Jingying Lin Si Chen Chunying Zhang Juan Liao Yuemei Chen Shanying Deng Zhigang Mao Tonghao Zhang Na Tian Yali Song Tingting Zeng |
| author_facet | Jingying Lin Si Chen Chunying Zhang Juan Liao Yuemei Chen Shanying Deng Zhigang Mao Tonghao Zhang Na Tian Yali Song Tingting Zeng |
| author_sort | Jingying Lin |
| collection | DOAJ |
| description | AbstractMicrofluidic technology has emerged as a powerful tool in studying arterial thrombosis, allowing researchers to construct artificial blood vessels and replicate the hemodynamics of blood flow. This technology has led to significant advancements in understanding thrombosis and platelet adhesion and aggregation. Microfluidic models have various types and functions, and by studying the fabrication methods and working principles of microfluidic chips, applicable methods can be selected according to specific needs. The rapid development of microfluidic integrated system and modular microfluidic system makes arterial thrombosis research more diversified and automated, but its standardization still needs to be solved urgently. One key advantage of microfluidic technology is the ability to precisely control fluid flow in microchannels and to analyze platelet behavior under different shear forces and flow rates. This allows researchers to study the physiological and pathological processes of blood flow, shedding light on the underlying mechanisms of arterial thrombosis. In conclusion, microfluidic technology has revolutionized the study of arterial thrombosis by enabling the construction of artificial blood vessels and accurately reproducing hemodynamics. In the future, microfluidics will place greater emphasis on versatility and automation, holding great promise for advancing antithrombotic therapeutic and prophylactic measures. |
| first_indexed | 2024-03-07T22:49:58Z |
| format | Article |
| id | doaj.art-f077268aed874a17886f7f01a32dcce6 |
| institution | Directory Open Access Journal |
| issn | 0953-7104 1369-1635 |
| language | English |
| last_indexed | 2024-03-07T22:49:58Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Platelets |
| spelling | doaj.art-f077268aed874a17886f7f01a32dcce62024-02-23T11:28:18ZengTaylor & Francis GroupPlatelets0953-71041369-16352024-12-0135110.1080/09537104.2024.2316743Recent advances in microfluidic technology of arterial thrombosis investigationsJingying Lin0Si Chen1Chunying Zhang2Juan Liao3Yuemei Chen4Shanying Deng5Zhigang Mao6Tonghao Zhang7Na Tian8Yali Song9Tingting Zeng10Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Statistics, University of Virginia, Charlottesville, USAAnesthesiology Department, Qingdao Eighth People’s Hospital, Qingdao, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, ChinaAbstractMicrofluidic technology has emerged as a powerful tool in studying arterial thrombosis, allowing researchers to construct artificial blood vessels and replicate the hemodynamics of blood flow. This technology has led to significant advancements in understanding thrombosis and platelet adhesion and aggregation. Microfluidic models have various types and functions, and by studying the fabrication methods and working principles of microfluidic chips, applicable methods can be selected according to specific needs. The rapid development of microfluidic integrated system and modular microfluidic system makes arterial thrombosis research more diversified and automated, but its standardization still needs to be solved urgently. One key advantage of microfluidic technology is the ability to precisely control fluid flow in microchannels and to analyze platelet behavior under different shear forces and flow rates. This allows researchers to study the physiological and pathological processes of blood flow, shedding light on the underlying mechanisms of arterial thrombosis. In conclusion, microfluidic technology has revolutionized the study of arterial thrombosis by enabling the construction of artificial blood vessels and accurately reproducing hemodynamics. In the future, microfluidics will place greater emphasis on versatility and automation, holding great promise for advancing antithrombotic therapeutic and prophylactic measures.https://www.tandfonline.com/doi/10.1080/09537104.2024.2316743Antithrombotic therapyarterial thrombosismicrofluidic chipmicrofluidic technologyplatelet aggregation |
| spellingShingle | Jingying Lin Si Chen Chunying Zhang Juan Liao Yuemei Chen Shanying Deng Zhigang Mao Tonghao Zhang Na Tian Yali Song Tingting Zeng Recent advances in microfluidic technology of arterial thrombosis investigations Platelets Antithrombotic therapy arterial thrombosis microfluidic chip microfluidic technology platelet aggregation |
| title | Recent advances in microfluidic technology of arterial thrombosis investigations |
| title_full | Recent advances in microfluidic technology of arterial thrombosis investigations |
| title_fullStr | Recent advances in microfluidic technology of arterial thrombosis investigations |
| title_full_unstemmed | Recent advances in microfluidic technology of arterial thrombosis investigations |
| title_short | Recent advances in microfluidic technology of arterial thrombosis investigations |
| title_sort | recent advances in microfluidic technology of arterial thrombosis investigations |
| topic | Antithrombotic therapy arterial thrombosis microfluidic chip microfluidic technology platelet aggregation |
| url | https://www.tandfonline.com/doi/10.1080/09537104.2024.2316743 |
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