High-Throughput Chemical Screening for Inhibitors of Salmonella Pathogenicity Island 2

Summary: Anti-virulence therapies are under active investigation as antibiotic alternatives; however, their identification from large-scale chemical libraries poses a unique challenge. The dispensability of virulence factors for growth in vitro precludes conventional, optical density-based screening...

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Bibliographic Details
Main Authors: Caressa N. Tsai, Brian K. Coombes
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:STAR Protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720300447