Expression of erythropoietin and its receptor increases in colonic neoplastic progression: The role of hypoxia in tumorigenesis

Expression of erythropoietin and its receptor increases in colonic neoplastic progression: The role of hypoxia in tumorigenesis

Background: Tissue hypoxia is a characteristic patho-physiologic property of colorectal cancer. This process may also add to a therapeutic problem of solid tumor resistance to chemo- and radiation therapy. Erythropoietin (Epo) expression is induced by tissue hypoxia. Acting via its receptor (EpoR),...

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Bibliographic Details
Main Authors: Zoltan Gombos, Ludovit Danihel, Vanda Repiska, Geza Acs, Emma Furth
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Colon cancer progression
erythropoietin receptor
erythropoietin
hypoxia
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=2;spage=273;epage=278;aulast=Gombos

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