In-vivo real-time control of protein expression from endogenous and synthetic gene networks.

In-vivo real-time control of protein expression from endogenous and synthetic gene networks.

We describe an innovative experimental and computational approach to control the expression of a protein in a population of yeast cells. We designed a simple control algorithm to automatically regulate the administration of inducer molecules to the cells by comparing the actual protein expression le...

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Podrobná bibliografie
Hlavní autoři: Filippo Menolascina, Gianfranco Fiore, Emanuele Orabona, Luca De Stefano, Mike Ferry, Jeff Hasty, Mario di Bernardo, Diego di Bernardo
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2014-05-01
Edice:PLoS Computational Biology
On-line přístup:http://europepmc.org/articles/PMC4022480?pdf=render

Internet

http://europepmc.org/articles/PMC4022480?pdf=render

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