Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case
Background: Patients with ulcerative colitis (UC) often exhibit susceptibilities to multiple autoimmune diseases such as Sjogren's syndrome, primary sclerosing cholangitis, systemic lupus erythematosus, and insulin-dependent diabetes mellitus. This propensity likely stems from common pathogenic...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Journal of Translational Autoimmunity |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589909023000382 |
| _version_ | 1797360007436566528 |
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| author | Jiaqi Zhao Fangxiao Liu Lingshuo Bai Zheng Jiao Zihui Meng Bo Jia Yu Huang Lin Liu |
| author_facet | Jiaqi Zhao Fangxiao Liu Lingshuo Bai Zheng Jiao Zihui Meng Bo Jia Yu Huang Lin Liu |
| author_sort | Jiaqi Zhao |
| collection | DOAJ |
| description | Background: Patients with ulcerative colitis (UC) often exhibit susceptibilities to multiple autoimmune diseases such as Sjogren's syndrome, primary sclerosing cholangitis, systemic lupus erythematosus, and insulin-dependent diabetes mellitus. This propensity likely stems from common pathogenic mechanisms underlying immune-mediated conditions. This report highlights the occurrence of autoimmune thyroid disease during UC exacerbations. Notably, the patient displayed petrified auricles.Case Summary.A 57-year-old male complained of sustained abdominal pain, diarrhea, hematochezia, and mucus for a duration of 20 days. The diagnosis of UC was confirmed via colonoscopy, histopathological examination, and small bowel MRE. Clinical evaluations revealed bilateral ectopic ossification in his ears, which appeared to develop over an unspecified timeframe. Imaging and histological evaluations substantiated the ectopic ossification diagnosis while eliminating the possibility of adrenal insufficiency. The presented case offers a unique instance of bilateral auricular ossification, which is hypothesized to result from hyperthyroidism. Conclusion: Our case report underscores the necessity of enhancing awareness of the rare complications associated with UC. Medical practitioners should recognize the potential overlap of autoimmune thyroid disorders in UC patients. It is imperative to test for thyroid-related antibodies in such individuals, irrespective of overt thyroid dysfunction. |
| first_indexed | 2024-03-08T15:32:09Z |
| format | Article |
| id | doaj.art-f07a170a82c3409284e27bb41765ee97 |
| institution | Directory Open Access Journal |
| issn | 2589-9090 |
| language | English |
| last_indexed | 2024-03-08T15:32:09Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Translational Autoimmunity |
| spelling | doaj.art-f07a170a82c3409284e27bb41765ee972024-01-10T04:39:15ZengElsevierJournal of Translational Autoimmunity2589-90902024-06-018100225Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a caseJiaqi Zhao0Fangxiao Liu1Lingshuo Bai2Zheng Jiao3Zihui Meng4Bo Jia5Yu Huang6Lin Liu7Department of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, ChinaLiaoning University of Traditional Chinese Medicine, Shenyang, ChinaLiaoning University of Traditional Chinese Medicine, Shenyang, ChinaDepartment of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, ChinaDepartment of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, ChinaDepartment of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, ChinaDepartment of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China; Corresponding author.Background: Patients with ulcerative colitis (UC) often exhibit susceptibilities to multiple autoimmune diseases such as Sjogren's syndrome, primary sclerosing cholangitis, systemic lupus erythematosus, and insulin-dependent diabetes mellitus. This propensity likely stems from common pathogenic mechanisms underlying immune-mediated conditions. This report highlights the occurrence of autoimmune thyroid disease during UC exacerbations. Notably, the patient displayed petrified auricles.Case Summary.A 57-year-old male complained of sustained abdominal pain, diarrhea, hematochezia, and mucus for a duration of 20 days. The diagnosis of UC was confirmed via colonoscopy, histopathological examination, and small bowel MRE. Clinical evaluations revealed bilateral ectopic ossification in his ears, which appeared to develop over an unspecified timeframe. Imaging and histological evaluations substantiated the ectopic ossification diagnosis while eliminating the possibility of adrenal insufficiency. The presented case offers a unique instance of bilateral auricular ossification, which is hypothesized to result from hyperthyroidism. Conclusion: Our case report underscores the necessity of enhancing awareness of the rare complications associated with UC. Medical practitioners should recognize the potential overlap of autoimmune thyroid disorders in UC patients. It is imperative to test for thyroid-related antibodies in such individuals, irrespective of overt thyroid dysfunction.http://www.sciencedirect.com/science/article/pii/S2589909023000382Ulcerative colitisAutoimmune thyroid diseaseHyperthyroidismPetrified pinna |
| spellingShingle | Jiaqi Zhao Fangxiao Liu Lingshuo Bai Zheng Jiao Zihui Meng Bo Jia Yu Huang Lin Liu Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case Journal of Translational Autoimmunity Ulcerative colitis Autoimmune thyroid disease Hyperthyroidism Petrified pinna |
| title | Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case |
| title_full | Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case |
| title_fullStr | Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case |
| title_full_unstemmed | Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case |
| title_short | Ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans：a case |
| title_sort | ulcerative colitis with autoimmune thyroid disease results in bilateral auricular ossificans a case |
| topic | Ulcerative colitis Autoimmune thyroid disease Hyperthyroidism Petrified pinna |
| url | http://www.sciencedirect.com/science/article/pii/S2589909023000382 |
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