CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China
Abstract Background Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients wit...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-04-01
|
| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12967-020-02324-w |
| _version_ | 1818882268847931392 |
|---|---|
| author | Xiaoming Li Wenbing Zeng Xiang Li Haonan Chen Linping Shi Xinghui Li Hongnian Xiang Yang Cao Hui Chen Chen Liu Jian Wang |
| author_facet | Xiaoming Li Wenbing Zeng Xiang Li Haonan Chen Linping Shi Xinghui Li Hongnian Xiang Yang Cao Hui Chen Chen Liu Jian Wang |
| author_sort | Xiaoming Li |
| collection | DOAJ |
| description | Abstract Background Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection in southwest China. Methods In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed. Results A total of 100 (76%) patients had a history of close contact with people living in Wuhan, Hubei. The clinical manifestations of COVID-19 included cough, fever. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved, 20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening, hydrothorax, pericardial effusion, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes. Conclusion Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time. |
| first_indexed | 2024-12-19T15:15:04Z |
| format | Article |
| id | doaj.art-f07ad67267284154865a4944240b6dca |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-12-19T15:15:04Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-f07ad67267284154865a4944240b6dca2022-12-21T20:16:10ZengBMCJournal of Translational Medicine1479-58762020-04-011811810.1186/s12967-020-02324-wCT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest ChinaXiaoming Li0Wenbing Zeng1Xiang Li2Haonan Chen3Linping Shi4Xinghui Li5Hongnian Xiang6Yang Cao7Hui Chen8Chen Liu9Jian Wang10Department of Radiology, First Affiliated Hospital to Army Medical UniversityDepartment of Radiology, Three Gorges Central HospitalDepartment of Radiology, Three Gorges Central HospitalDepartment of Radiology, Three Gorges Central HospitalDepartment of Radiology, Hubei Provincial Corps Hospital Chinese People’s Armed Police ForcesDepartment of Radiology, Affiliated Hospital of North Sichuan Medical CollegeDepartment of Radiology, Chongqing Wuxi County People’s HospitalDepartment of Radiology, Dianjiang People’s Hospital of ChongqingDepartment of Radiology, First Affiliated Hospital to Army Medical UniversityDepartment of Radiology, First Affiliated Hospital to Army Medical UniversityDepartment of Radiology, First Affiliated Hospital to Army Medical UniversityAbstract Background Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection in southwest China. Methods In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed. Results A total of 100 (76%) patients had a history of close contact with people living in Wuhan, Hubei. The clinical manifestations of COVID-19 included cough, fever. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved, 20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening, hydrothorax, pericardial effusion, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes. Conclusion Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time.http://link.springer.com/article/10.1186/s12967-020-02324-wCoronavirusThe chestComputed tomographyPneumoniaEvolvement |
| spellingShingle | Xiaoming Li Wenbing Zeng Xiang Li Haonan Chen Linping Shi Xinghui Li Hongnian Xiang Yang Cao Hui Chen Chen Liu Jian Wang CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China Journal of Translational Medicine Coronavirus The chest Computed tomography Pneumonia Evolvement |
| title | CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China |
| title_full | CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China |
| title_fullStr | CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China |
| title_full_unstemmed | CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China |
| title_short | CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China |
| title_sort | ct imaging changes of corona virus disease 2019 covid 19 a multi center study in southwest china |
| topic | Coronavirus The chest Computed tomography Pneumonia Evolvement |
| url | http://link.springer.com/article/10.1186/s12967-020-02324-w |
| work_keys_str_mv | AT xiaomingli ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT wenbingzeng ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT xiangli ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT haonanchen ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT linpingshi ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT xinghuili ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT hongnianxiang ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT yangcao ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT huichen ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT chenliu ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina AT jianwang ctimagingchangesofcoronavirusdisease2019covid19amulticenterstudyinsouthwestchina |