CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative insecticides is advocated for indoor residual spraying (IRS), and carbamates are increasingly important. Emergence of a...

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Bibliographic Details
Main Authors: Constant V Edi, Luc Djogbénou, Adam M Jenkins, Kimberly Regna, Marc A T Muskavitch, Rodolphe Poupardin, Christopher M Jones, John Essandoh, Guillaume K Kétoh, Mark J I Paine, Benjamin G Koudou, Martin J Donnelly, Hilary Ranson, David Weetman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3961184?pdf=render