Targeted Radionuclide Therapy

Targeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relat...

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Main Authors: David Cheng, Devrim Ersahin, Indukala Doddamane
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/4/3838/
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author David Cheng
Devrim Ersahin
Indukala Doddamane
author_facet David Cheng
Devrim Ersahin
Indukala Doddamane
author_sort David Cheng
collection DOAJ
description Targeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the possibility of assessing the uptake by the tumor prior to the therapy. Several different radiopharmaceuticals are currently being used by various administration routes and targeting mechanisms. This article aims to briefly review the current status of targeted radiotherapy as well as to outline the advantages and disadvantages of radionuclides used for this purpose.
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spelling doaj.art-f07c065f9a0544969236757db1bd3f912023-09-02T06:05:29ZengMDPI AGCancers2072-66942011-10-01343838385510.3390/cancers3043838Targeted Radionuclide TherapyDavid ChengDevrim ErsahinIndukala DoddamaneTargeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the possibility of assessing the uptake by the tumor prior to the therapy. Several different radiopharmaceuticals are currently being used by various administration routes and targeting mechanisms. This article aims to briefly review the current status of targeted radiotherapy as well as to outline the advantages and disadvantages of radionuclides used for this purpose.http://www.mdpi.com/2072-6694/3/4/3838/targeted radiotherapyradionuclideradioimmunotherapy
spellingShingle David Cheng
Devrim Ersahin
Indukala Doddamane
Targeted Radionuclide Therapy
Cancers
targeted radiotherapy
radionuclide
radioimmunotherapy
title Targeted Radionuclide Therapy
title_full Targeted Radionuclide Therapy
title_fullStr Targeted Radionuclide Therapy
title_full_unstemmed Targeted Radionuclide Therapy
title_short Targeted Radionuclide Therapy
title_sort targeted radionuclide therapy
topic targeted radiotherapy
radionuclide
radioimmunotherapy
url http://www.mdpi.com/2072-6694/3/4/3838/
work_keys_str_mv AT davidcheng targetedradionuclidetherapy
AT devrimersahin targetedradionuclidetherapy
AT indukaladoddamane targetedradionuclidetherapy