Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats
The aim of this study was to evaluate the effect of in vivo treatment with an aqueous cinnamon extract on the labeling of blood constituents with 99mTc and on the morphology of red blood cells from Wistar rats. Animals were treated with cinnamon extract at different doses and for different periods o...
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2008-12-01
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| Series: | Brazilian Archives of Biology and Technology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700023 |
| _version_ | 1819056881006542848 |
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| author | Mônica Oliveira Benarroz Gabrielle de Souza Rocha Márcia Oliveira Pereira Mauro Geller Adenilson de Souza da Fonseca Giuseppe Antonio Presta Mario Bernardo-Filho |
| author_facet | Mônica Oliveira Benarroz Gabrielle de Souza Rocha Márcia Oliveira Pereira Mauro Geller Adenilson de Souza da Fonseca Giuseppe Antonio Presta Mario Bernardo-Filho |
| author_sort | Mônica Oliveira Benarroz |
| collection | DOAJ |
| description | The aim of this study was to evaluate the effect of in vivo treatment with an aqueous cinnamon extract on the labeling of blood constituents with 99mTc and on the morphology of red blood cells from Wistar rats. Animals were treated with cinnamon extract at different doses and for different periods of time. As controls, animals treated with 0.9% NaCl. Labeling of blood constituents with 99mTc was performed. Plasma, blood cells and insoluble fractions were isolated. Radioactivity in each fraction was counted and the percentage of radioactivity (%ATI) was calculated. Also, blood smears were prepared to morphological analysis of red blood cells from. Data showed that in vivo cinnamon extract did not significantly (p>0.05) modify the %ATI of blood constituents and morphology of red blood cells. The results suggest that in vivo aqueous cinnamon could not affect the membrane structures involved in transport of ions or the oxidation state of stannous and pertechnetate ions.<br>O objetivo deste estudo foi avaliar efeitos do tratamento in vivo com um extrato aquoso de canela na marcação de constituintes sangüíneos com 99mTc e na morfologia de hemácias de ratos Wistar. Os animais foram tratados com diferentes doses ou por diferentes tempos com extrato de canela Como controles, animais tratados com NaCl 0,9%. A marcação de constituintes sangüíneos com 99mTc foi realizada, plasma, células sangüíneas e frações insolúveis foram isoladas. A radioatividade em cada fração foi contada e a porcentagem de radioatividade (%ATI) foi calculada. Distensões sangüíneas foram preparadas para análise morfológica de hemácias. Os dados mostraram que o tratamento in vivo com extrato de canela não modificaria significativamente (p>0,05) a %ATI nos constituintes sangüíneos e a morfologia de hemácias. Os resultados sugerem que o extrato aquoso de canela não afetaria in vivo as estruturas da membrana envolvidas no transporte de íons ou o estado de oxidação dos íons estanoso e pertecnetato. |
| first_indexed | 2024-12-21T13:30:27Z |
| format | Article |
| id | doaj.art-f07ce59a91894c37bbbe34364ed333db |
| institution | Directory Open Access Journal |
| issn | 1516-8913 1678-4324 |
| language | English |
| last_indexed | 2024-12-21T13:30:27Z |
| publishDate | 2008-12-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-f07ce59a91894c37bbbe34364ed333db2022-12-21T19:02:20ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43242008-12-0151spe14314910.1590/S1516-89132008000700023Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar ratsMônica Oliveira BenarrozGabrielle de Souza RochaMárcia Oliveira PereiraMauro GellerAdenilson de Souza da FonsecaGiuseppe Antonio PrestaMario Bernardo-FilhoThe aim of this study was to evaluate the effect of in vivo treatment with an aqueous cinnamon extract on the labeling of blood constituents with 99mTc and on the morphology of red blood cells from Wistar rats. Animals were treated with cinnamon extract at different doses and for different periods of time. As controls, animals treated with 0.9% NaCl. Labeling of blood constituents with 99mTc was performed. Plasma, blood cells and insoluble fractions were isolated. Radioactivity in each fraction was counted and the percentage of radioactivity (%ATI) was calculated. Also, blood smears were prepared to morphological analysis of red blood cells from. Data showed that in vivo cinnamon extract did not significantly (p>0.05) modify the %ATI of blood constituents and morphology of red blood cells. The results suggest that in vivo aqueous cinnamon could not affect the membrane structures involved in transport of ions or the oxidation state of stannous and pertechnetate ions.<br>O objetivo deste estudo foi avaliar efeitos do tratamento in vivo com um extrato aquoso de canela na marcação de constituintes sangüíneos com 99mTc e na morfologia de hemácias de ratos Wistar. Os animais foram tratados com diferentes doses ou por diferentes tempos com extrato de canela Como controles, animais tratados com NaCl 0,9%. A marcação de constituintes sangüíneos com 99mTc foi realizada, plasma, células sangüíneas e frações insolúveis foram isoladas. A radioatividade em cada fração foi contada e a porcentagem de radioatividade (%ATI) foi calculada. Distensões sangüíneas foram preparadas para análise morfológica de hemácias. Os dados mostraram que o tratamento in vivo com extrato de canela não modificaria significativamente (p>0,05) a %ATI nos constituintes sangüíneos e a morfologia de hemácias. Os resultados sugerem que o extrato aquoso de canela não afetaria in vivo as estruturas da membrana envolvidas no transporte de íons ou o estado de oxidação dos íons estanoso e pertecnetato.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700023blood constituentsCinnamomum zeylanicumtechnetium-99m |
| spellingShingle | Mônica Oliveira Benarroz Gabrielle de Souza Rocha Márcia Oliveira Pereira Mauro Geller Adenilson de Souza da Fonseca Giuseppe Antonio Presta Mario Bernardo-Filho Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats Brazilian Archives of Biology and Technology blood constituents Cinnamomum zeylanicum technetium-99m |
| title | Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats |
| title_full | Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats |
| title_fullStr | Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats |
| title_full_unstemmed | Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats |
| title_short | Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats |
| title_sort | effects of cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in wistar rats |
| topic | blood constituents Cinnamomum zeylanicum technetium-99m |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700023 |
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