Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy

Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy

BackgroundIn cardiac hypertrophy and failure, there is a widespread alteration in mRNA splicing, but the role of splice variants in cardiac hypertrophy has not yet been fully elucidated. In this study, we used an exon array to identify novel splice variants associated with cardiac hypertrophy. Metho...

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Bibliographic Details
Main Authors: Shin Ito, Masanori Asakura, Yulin Liao, Kyung‐Duk Min, Ayako Takahashi, Kazuhiro Shindo, Satoru Yamazaki, Osamu Tsukamoto, Hiroshi Asanuma, Masaki Mogi, Masatsugu Horiuchi, Yoshihiro Asano, Shoji Sanada, Tetsuo Minamino, Seiji Takashima, Naoki Mochizuki, Masafumi Kitakaze
Format: Article
Language:English
Published: Wiley 2016-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac hypertrophy
gene array
gene expression/regulation
molecular biology
splice variant
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.003521

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