Synthetic cells with self-activating optogenetic proteins communicate with natural cells
Synthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication.
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29871-8 |
| _version_ | 1811338838223618048 |
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| author | Omer Adir Mia R. Albalak Ravit Abel Lucien E. Weiss Gal Chen Amit Gruber Oskar Staufer Yaniv Kurman Ido Kaminer Jeny Shklover Janna Shainsky-Roitman Ilia Platzman Lior Gepstein Yoav Shechtman Benjamin A. Horwitz Avi Schroeder |
| author_facet | Omer Adir Mia R. Albalak Ravit Abel Lucien E. Weiss Gal Chen Amit Gruber Oskar Staufer Yaniv Kurman Ido Kaminer Jeny Shklover Janna Shainsky-Roitman Ilia Platzman Lior Gepstein Yoav Shechtman Benjamin A. Horwitz Avi Schroeder |
| author_sort | Omer Adir |
| collection | DOAJ |
| description | Synthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication. |
| first_indexed | 2024-04-13T18:16:32Z |
| format | Article |
| id | doaj.art-f081c2771b204a69ba9f89ea10bf1504 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T18:16:32Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f081c2771b204a69ba9f89ea10bf15042022-12-22T02:35:39ZengNature PortfolioNature Communications2041-17232022-04-0113111310.1038/s41467-022-29871-8Synthetic cells with self-activating optogenetic proteins communicate with natural cellsOmer Adir0Mia R. Albalak1Ravit Abel2Lucien E. Weiss3Gal Chen4Amit Gruber5Oskar Staufer6Yaniv Kurman7Ido Kaminer8Jeny Shklover9Janna Shainsky-Roitman10Ilia Platzman11Lior Gepstein12Yoav Shechtman13Benjamin A. Horwitz14Avi Schroeder15The Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionDepartment of Biomedical Engineering, TechnionThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionSohnis Research Laboratory for Cardiac Electrophysiology and Regenerative Medicine, the Rappaport Faculty of Medicine and Research Institute, TechnionDepartment for Cellular Biophysics, Max Planck Institute for Medical ResearchThe Andrew and Erna Viterbi Faculty of Electrical and Computer Engineering, TechnionThe Andrew and Erna Viterbi Faculty of Electrical and Computer Engineering, TechnionThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionDepartment for Cellular Biophysics, Max Planck Institute for Medical ResearchSohnis Research Laboratory for Cardiac Electrophysiology and Regenerative Medicine, the Rappaport Faculty of Medicine and Research Institute, TechnionDepartment of Biomedical Engineering, TechnionFaculty of Biology, Technion - Israel Institute of TechnologyThe Louis Family Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Department of Chemical Engineering, TechnionSynthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication.https://doi.org/10.1038/s41467-022-29871-8 |
| spellingShingle | Omer Adir Mia R. Albalak Ravit Abel Lucien E. Weiss Gal Chen Amit Gruber Oskar Staufer Yaniv Kurman Ido Kaminer Jeny Shklover Janna Shainsky-Roitman Ilia Platzman Lior Gepstein Yoav Shechtman Benjamin A. Horwitz Avi Schroeder Synthetic cells with self-activating optogenetic proteins communicate with natural cells Nature Communications |
| title | Synthetic cells with self-activating optogenetic proteins communicate with natural cells |
| title_full | Synthetic cells with self-activating optogenetic proteins communicate with natural cells |
| title_fullStr | Synthetic cells with self-activating optogenetic proteins communicate with natural cells |
| title_full_unstemmed | Synthetic cells with self-activating optogenetic proteins communicate with natural cells |
| title_short | Synthetic cells with self-activating optogenetic proteins communicate with natural cells |
| title_sort | synthetic cells with self activating optogenetic proteins communicate with natural cells |
| url | https://doi.org/10.1038/s41467-022-29871-8 |
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