The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia
Aims: To evaluate the effects of melatonin premedication on anxiety and pain scores of patients, operating conditions, and intraocular pressure during cataract surgery under topical anesthesia. Materials and Methods: Sixty patients were randomly assigned to receive either sublingual melatonin 3 mg o...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
|
| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=7;spage=319;epage=324;aulast=Khezri |
| _version_ | 1819207244413140992 |
|---|---|
| author | Marzieh Beigom Khezri Hamid Merate |
| author_facet | Marzieh Beigom Khezri Hamid Merate |
| author_sort | Marzieh Beigom Khezri |
| collection | DOAJ |
| description | Aims: To evaluate the effects of melatonin premedication on anxiety and pain scores of patients, operating conditions, and intraocular pressure during cataract surgery under topical anesthesia. Materials and Methods: Sixty patients were randomly assigned to receive either sublingual melatonin 3 mg or placebo 60 min before surgery. Verbal anxiety scores and verbal pain scores, heart rate, systolic and diastolic blood pressure, intraocular pressure, and quality of operating conditions were recorded. Results: Melatonin significantly reduced the anxiety scores (median, interquartile range) from 5 and 5-3 to 3 and 2-4 after premedication and to 3 and 2-3 during surgery and to 0 and 0-1 postoperatively before discharge from the recovery room. There were significant differences between two groups in anxiety scores after premedication (95% CI 3-3.5; P = 0.023), intraoperatively (95% CI 2.5-3.5; P = 0.007), and postoperatively (95% CI 0.5-1; P = 0.007). The surgeon reported better quality of operating conditions in the melatonin group (P = 0.001). No significant difference in intraoperative and postoperative pain scores, intraocular pressure, heart rate, and systolic and diastolic blood pressure between two groups was recorded. Conclusion: Sublingual melatonin premedication for patients undergoing cataract surgery under topical anesthesia reduced the anxiety scores in patients and provided excellent operating conditions. |
| first_indexed | 2024-12-23T05:20:25Z |
| format | Article |
| id | doaj.art-f08316be29eb41b6a51c317be9f55bbb |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-23T05:20:25Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-f08316be29eb41b6a51c317be9f55bbb2022-12-21T17:58:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-0161731932410.4103/0301-4738.99637The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesiaMarzieh Beigom KhezriHamid MerateAims: To evaluate the effects of melatonin premedication on anxiety and pain scores of patients, operating conditions, and intraocular pressure during cataract surgery under topical anesthesia. Materials and Methods: Sixty patients were randomly assigned to receive either sublingual melatonin 3 mg or placebo 60 min before surgery. Verbal anxiety scores and verbal pain scores, heart rate, systolic and diastolic blood pressure, intraocular pressure, and quality of operating conditions were recorded. Results: Melatonin significantly reduced the anxiety scores (median, interquartile range) from 5 and 5-3 to 3 and 2-4 after premedication and to 3 and 2-3 during surgery and to 0 and 0-1 postoperatively before discharge from the recovery room. There were significant differences between two groups in anxiety scores after premedication (95% CI 3-3.5; P = 0.023), intraoperatively (95% CI 2.5-3.5; P = 0.007), and postoperatively (95% CI 0.5-1; P = 0.007). The surgeon reported better quality of operating conditions in the melatonin group (P = 0.001). No significant difference in intraoperative and postoperative pain scores, intraocular pressure, heart rate, and systolic and diastolic blood pressure between two groups was recorded. Conclusion: Sublingual melatonin premedication for patients undergoing cataract surgery under topical anesthesia reduced the anxiety scores in patients and provided excellent operating conditions.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=7;spage=319;epage=324;aulast=KhezriAnxietycataractintraocular pressuremelatoninpaintopical anesthesia |
| spellingShingle | Marzieh Beigom Khezri Hamid Merate The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia Indian Journal of Ophthalmology Anxiety cataract intraocular pressure melatonin pain topical anesthesia |
| title | The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia |
| title_full | The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia |
| title_fullStr | The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia |
| title_full_unstemmed | The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia |
| title_short | The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia |
| title_sort | effects of melatonin on anxiety and pain scores of patients intraocular pressure and operating conditions during cataract surgery under topical anesthesia |
| topic | Anxiety cataract intraocular pressure melatonin pain topical anesthesia |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=7;spage=319;epage=324;aulast=Khezri |
| work_keys_str_mv | AT marziehbeigomkhezri theeffectsofmelatoninonanxietyandpainscoresofpatientsintraocularpressureandoperatingconditionsduringcataractsurgeryundertopicalanesthesia AT hamidmerate theeffectsofmelatoninonanxietyandpainscoresofpatientsintraocularpressureandoperatingconditionsduringcataractsurgeryundertopicalanesthesia AT marziehbeigomkhezri effectsofmelatoninonanxietyandpainscoresofpatientsintraocularpressureandoperatingconditionsduringcataractsurgeryundertopicalanesthesia AT hamidmerate effectsofmelatoninonanxietyandpainscoresofpatientsintraocularpressureandoperatingconditionsduringcataractsurgeryundertopicalanesthesia |