Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?

Creatine monohydrate (CM) is an established and effective dietary supplement, but it is not the only form of creatine. We analyzed forms of creatine for sale on Amazon.com'' title = ''http://Amazon.com''>Amazon.com and evaluated if the advertised claims are supported...

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Main Authors: Guillermo Escalante, Adam M. Gonzalez, Dean St Mart, Michael Torres, Jacob Echols, Mariesha Islas, Brad J. Schoenfeld
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022034016
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author Guillermo Escalante
Adam M. Gonzalez
Dean St Mart
Michael Torres
Jacob Echols
Mariesha Islas
Brad J. Schoenfeld
author_facet Guillermo Escalante
Adam M. Gonzalez
Dean St Mart
Michael Torres
Jacob Echols
Mariesha Islas
Brad J. Schoenfeld
author_sort Guillermo Escalante
collection DOAJ
description Creatine monohydrate (CM) is an established and effective dietary supplement, but it is not the only form of creatine. We analyzed forms of creatine for sale on Amazon.com'' title = ''http://Amazon.com''>Amazon.com and evaluated if the advertised claims are supported by the available scientific evidence. We also analyzed the cost per gram of the forms of creatine. A total of 175 creatine supplements were included and we reported the total creatine content per serving, form(s) of creatine in products, product claims, and prevalence of products third party certified. The identified products contained 16 forms of creatine other than CM. The prevalence of products containing functional ingredients with CM or forms of creatine was 29.7%, and the prevalence of products containing blends of different forms of creatine was 21.7%. Only 8% of products were third party certified. The products using only CM (n = 91) had a mean price per gram of $0.12 ± 0.08, whereas products using only other forms of creatine (n = 32) had a mean price per gram of $0.26 ± 0.17. Approximately 88% of alternative creatine products in this study are classified as having limited to no evidence to support bioavailability, efficacy, and safety.
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spelling doaj.art-f08976c94eed406283961c7eb72ab5d62023-01-05T08:38:43ZengElsevierHeliyon2405-84402022-12-01812e12113Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?Guillermo Escalante0Adam M. Gonzalez1Dean St Mart2Michael Torres3Jacob Echols4Mariesha Islas5Brad J. Schoenfeld6California State University San Bernardino, USA; Corresponding author.Hofstra University, USASupplement Needs, United KingdomCalifornia State University San Bernardino, USACalifornia State University San Bernardino, USACalifornia State University San Bernardino, USACUNY Lehman College, USACreatine monohydrate (CM) is an established and effective dietary supplement, but it is not the only form of creatine. We analyzed forms of creatine for sale on Amazon.com'' title = ''http://Amazon.com''>Amazon.com and evaluated if the advertised claims are supported by the available scientific evidence. We also analyzed the cost per gram of the forms of creatine. A total of 175 creatine supplements were included and we reported the total creatine content per serving, form(s) of creatine in products, product claims, and prevalence of products third party certified. The identified products contained 16 forms of creatine other than CM. The prevalence of products containing functional ingredients with CM or forms of creatine was 29.7%, and the prevalence of products containing blends of different forms of creatine was 21.7%. Only 8% of products were third party certified. The products using only CM (n = 91) had a mean price per gram of $0.12 ± 0.08, whereas products using only other forms of creatine (n = 32) had a mean price per gram of $0.26 ± 0.17. Approximately 88% of alternative creatine products in this study are classified as having limited to no evidence to support bioavailability, efficacy, and safety.http://www.sciencedirect.com/science/article/pii/S2405844022034016SupplementationCreatine monohydrateMulti-ingredientFunctional ingredients
spellingShingle Guillermo Escalante
Adam M. Gonzalez
Dean St Mart
Michael Torres
Jacob Echols
Mariesha Islas
Brad J. Schoenfeld
Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
Heliyon
Supplementation
Creatine monohydrate
Multi-ingredient
Functional ingredients
title Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
title_full Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
title_fullStr Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
title_full_unstemmed Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
title_short Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?
title_sort analysis of the efficacy safety and cost of alternative forms of creatine available for purchase on amazon com are label claims supported by science
topic Supplementation
Creatine monohydrate
Multi-ingredient
Functional ingredients
url http://www.sciencedirect.com/science/article/pii/S2405844022034016
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