Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry
Irritability is a core symptom of adolescent depression, characterized by an increased proneness to anger or frustration. Irritability in youth is associated with future mental health problems and impaired social functioning, suggesting that it may be an early indicator of emotion regulation difficu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1124940/full |
| _version_ | 1797803832582864896 |
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| author | Niamh MacSweeney Niamh MacSweeney Niamh MacSweeney Perrine Louvet Simal Zafar Stella W. Y. Chan Alex S. F. Kwong Alex S. F. Kwong Alex S. F. Kwong Stephen M. Lawrie Liana Romaniuk Heather C. Whalley Heather C. Whalley |
| author_facet | Niamh MacSweeney Niamh MacSweeney Niamh MacSweeney Perrine Louvet Simal Zafar Stella W. Y. Chan Alex S. F. Kwong Alex S. F. Kwong Alex S. F. Kwong Stephen M. Lawrie Liana Romaniuk Heather C. Whalley Heather C. Whalley |
| author_sort | Niamh MacSweeney |
| collection | DOAJ |
| description | Irritability is a core symptom of adolescent depression, characterized by an increased proneness to anger or frustration. Irritability in youth is associated with future mental health problems and impaired social functioning, suggesting that it may be an early indicator of emotion regulation difficulties. Adolescence is a period during which behavior is significantly impacted by one’s environment. However, existing research on the neural basis of irritability typically use experimental paradigms that overlook the social context in which irritability occurs. Here, we bring together current findings on irritability in adolescent depression and the associated neurobiology and highlight directions for future research. Specifically, we emphasize the importance of co-produced research with young people as a means to improve the construct and ecological validity of research within the field. Ensuring that our research design and methodology accurately reflect to lives of young people today lays a strong foundation upon which to better understand adolescent depression and identify tractable targets for intervention. |
| first_indexed | 2024-03-13T05:26:57Z |
| format | Article |
| id | doaj.art-f0898fb57a1f4e88bfa3c5268caf7cb7 |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-03-13T05:26:57Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-f0898fb57a1f4e88bfa3c5268caf7cb72023-06-15T05:39:18ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532023-06-011710.3389/fnbeh.2023.11249401124940Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitryNiamh MacSweeney0Niamh MacSweeney1Niamh MacSweeney2Perrine Louvet3Simal Zafar4Stella W. Y. Chan5Alex S. F. Kwong6Alex S. F. Kwong7Alex S. F. Kwong8Stephen M. Lawrie9Liana Romaniuk10Heather C. Whalley11Heather C. Whalley12Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, NorwayPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, NorwayDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomSchool of Life Sciences, University of Glasgow, Glasgow, United KingdomSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, United KingdomDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United KingdomPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United KingdomDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United KingdomGeneration Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United KingdomIrritability is a core symptom of adolescent depression, characterized by an increased proneness to anger or frustration. Irritability in youth is associated with future mental health problems and impaired social functioning, suggesting that it may be an early indicator of emotion regulation difficulties. Adolescence is a period during which behavior is significantly impacted by one’s environment. However, existing research on the neural basis of irritability typically use experimental paradigms that overlook the social context in which irritability occurs. Here, we bring together current findings on irritability in adolescent depression and the associated neurobiology and highlight directions for future research. Specifically, we emphasize the importance of co-produced research with young people as a means to improve the construct and ecological validity of research within the field. Ensuring that our research design and methodology accurately reflect to lives of young people today lays a strong foundation upon which to better understand adolescent depression and identify tractable targets for intervention.https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1124940/fullirritabilityadolescent depressionco-productionfMRIadolescence |
| spellingShingle | Niamh MacSweeney Niamh MacSweeney Niamh MacSweeney Perrine Louvet Simal Zafar Stella W. Y. Chan Alex S. F. Kwong Alex S. F. Kwong Alex S. F. Kwong Stephen M. Lawrie Liana Romaniuk Heather C. Whalley Heather C. Whalley Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry Frontiers in Behavioral Neuroscience irritability adolescent depression co-production fMRI adolescence |
| title | Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry |
| title_full | Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry |
| title_fullStr | Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry |
| title_full_unstemmed | Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry |
| title_short | Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry |
| title_sort | keeping up with the kids the value of co production in the study of irritability in youth depression and its underlying neural circuitry |
| topic | irritability adolescent depression co-production fMRI adolescence |
| url | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1124940/full |
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