KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010
Drug interactions are one of the Drug Related Problems (DRPs) that may affect patient treatment outcomes. Hypertension occurs in approximately 10% to 81.5% of hemodialysis patients. The purpose of this study was to determine the incidence of antihypertensive drug interactions in hemodialysis pati...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Universitas Ahmad Dahlan
2012-05-01
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| Series: | Pharmaciana |
| Subjects: | |
| Online Access: | http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/658/498 |
| _version_ | 1818657654029942784 |
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| author | Siti Rahmiati Woro Supadmi |
| author_facet | Siti Rahmiati Woro Supadmi |
| author_sort | Siti Rahmiati |
| collection | DOAJ |
| description | Drug interactions are one of the Drug Related Problems (DRPs) that may affect
patient treatment outcomes. Hypertension occurs in approximately 10% to 81.5% of
hemodialysis patients. The purpose of this study was to determine the incidence of
antihypertensive drug interactions in hemodialysis patients in the inpatient wards PKU
Muhammadiyah Hospital of Yogyakarta period in 2010. This study descriptive design.
Data retrieved retrospectively. Data retrieval were done by taking all the data that
meet the criteria of existing research on the medical records of hemodialysis patients in
PKU Muhammadiyah Hospital of Yogyakarta who received antihypertensive with
above normal blood pressure (= 130/80 mmHg). Data were analyzed based on the
descriptive level of significance, onset, and severity. The results showed that there were
54.79% (40 patients) of 73 hemodialysis patients potentially experienced drug
interactions. Antihypertensive drugs most widely used in hemodialysis patients were
ACEI, CCB, and diuretics. Incidence of antihypertensive drug interactions 27 cases
(45.76% were most common at a significance level 3, 48 cases (81.36%) were onset
delayed, and the severity minor of 44 cases (74.58%). The mechanism of interactions
pharmacodynamic were 37 cases (62.71%) of the total 59 events that have drug
interactions. Drugs often interactions were furosemide and captopril. |
| first_indexed | 2024-12-17T03:44:54Z |
| format | Article |
| id | doaj.art-f08da721350d4a668f5330a37bae61cd |
| institution | Directory Open Access Journal |
| issn | 2088-4559 2477-0256 |
| language | English |
| last_indexed | 2024-12-17T03:44:54Z |
| publishDate | 2012-05-01 |
| publisher | Universitas Ahmad Dahlan |
| record_format | Article |
| series | Pharmaciana |
| spelling | doaj.art-f08da721350d4a668f5330a37bae61cd2022-12-21T22:04:55ZengUniversitas Ahmad DahlanPharmaciana2088-45592477-02562012-05-01219711010.12928/pharmaciana.v2i1.658KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010Siti Rahmiati0Woro Supadmi1Universitas Ahmad DahlanUniversitas Ahmad DahlanDrug interactions are one of the Drug Related Problems (DRPs) that may affect patient treatment outcomes. Hypertension occurs in approximately 10% to 81.5% of hemodialysis patients. The purpose of this study was to determine the incidence of antihypertensive drug interactions in hemodialysis patients in the inpatient wards PKU Muhammadiyah Hospital of Yogyakarta period in 2010. This study descriptive design. Data retrieved retrospectively. Data retrieval were done by taking all the data that meet the criteria of existing research on the medical records of hemodialysis patients in PKU Muhammadiyah Hospital of Yogyakarta who received antihypertensive with above normal blood pressure (= 130/80 mmHg). Data were analyzed based on the descriptive level of significance, onset, and severity. The results showed that there were 54.79% (40 patients) of 73 hemodialysis patients potentially experienced drug interactions. Antihypertensive drugs most widely used in hemodialysis patients were ACEI, CCB, and diuretics. Incidence of antihypertensive drug interactions 27 cases (45.76% were most common at a significance level 3, 48 cases (81.36%) were onset delayed, and the severity minor of 44 cases (74.58%). The mechanism of interactions pharmacodynamic were 37 cases (62.71%) of the total 59 events that have drug interactions. Drugs often interactions were furosemide and captopril.http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/658/498drug interactionsantihypertensivehemodialysis |
| spellingShingle | Siti Rahmiati Woro Supadmi KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 Pharmaciana drug interactions antihypertensive hemodialysis |
| title | KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 |
| title_full | KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 |
| title_fullStr | KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 |
| title_full_unstemmed | KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 |
| title_short | KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 |
| title_sort | kajian interaksi obat antihipertensi pada pasien hemodialisis di bangsal rawat inap rsu pku muhammadiyah yogyakarta periode tahun 2010 |
| topic | drug interactions antihypertensive hemodialysis |
| url | http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/658/498 |
| work_keys_str_mv | AT sitirahmiati kajianinteraksiobatantihipertensipadapasienhemodialisisdibangsalrawatinaprsupkumuhammadiyahyogyakartaperiodetahun2010 AT worosupadmi kajianinteraksiobatantihipertensipadapasienhemodialisisdibangsalrawatinaprsupkumuhammadiyahyogyakartaperiodetahun2010 |