DNA Immunization for HIV Vaccine Development
DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future ou...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-02-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-393X/2/1/138 |
| _version_ | 1811263325577674752 |
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| author | Yuxin Chen Shixia Wang Shan Lu |
| author_facet | Yuxin Chen Shixia Wang Shan Lu |
| author_sort | Yuxin Chen |
| collection | DOAJ |
| description | DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development. |
| first_indexed | 2024-04-12T19:42:35Z |
| format | Article |
| id | doaj.art-f09097f477a340d2881a6529b797def1 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-04-12T19:42:35Z |
| publishDate | 2014-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-f09097f477a340d2881a6529b797def12022-12-22T03:19:02ZengMDPI AGVaccines2076-393X2014-02-012113815910.3390/vaccines2010138vaccines2010138DNA Immunization for HIV Vaccine DevelopmentYuxin Chen0Shixia Wang1Shan Lu2Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USADepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USADepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USADNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development.http://www.mdpi.com/2076-393X/2/1/138HIV-1AIDSvaccineDNA immunization |
| spellingShingle | Yuxin Chen Shixia Wang Shan Lu DNA Immunization for HIV Vaccine Development Vaccines HIV-1 AIDS vaccine DNA immunization |
| title | DNA Immunization for HIV Vaccine Development |
| title_full | DNA Immunization for HIV Vaccine Development |
| title_fullStr | DNA Immunization for HIV Vaccine Development |
| title_full_unstemmed | DNA Immunization for HIV Vaccine Development |
| title_short | DNA Immunization for HIV Vaccine Development |
| title_sort | dna immunization for hiv vaccine development |
| topic | HIV-1 AIDS vaccine DNA immunization |
| url | http://www.mdpi.com/2076-393X/2/1/138 |
| work_keys_str_mv | AT yuxinchen dnaimmunizationforhivvaccinedevelopment AT shixiawang dnaimmunizationforhivvaccinedevelopment AT shanlu dnaimmunizationforhivvaccinedevelopment |