Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review

Pleomorphic adenoma (PA) is a salivary gland tumour characterised microscopically by architectural rather than cellular pleomorphism. The neoplasm also has finger-like projections into the pseudocapsule, which clinically has attributed to the high recurrence rate associated with the neoplasm. Vascul...

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Main Author: E.N. Nokaneng
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Oral and Maxillofacial Surgery Cases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214541922000402
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author E.N. Nokaneng
author_facet E.N. Nokaneng
author_sort E.N. Nokaneng
collection DOAJ
description Pleomorphic adenoma (PA) is a salivary gland tumour characterised microscopically by architectural rather than cellular pleomorphism. The neoplasm also has finger-like projections into the pseudocapsule, which clinically has attributed to the high recurrence rate associated with the neoplasm. Vascular and neural invasion have been reported and are regarded as atypical features of the neoplasm. Review of the literature suggests that invasion of bone without malignant transformation by the neoplasm is very rare.A 28-year-old female was diagnosed with an invasive recurrent PA of the palate, which required en-bloc resection of the left maxilla. The computed tomography scan showed a homogeneous, well-defined, multilocular lesion which extended from the anterior to the posterior of the maxilla. The histological analysis did not report any malignant transformation of the lesion. Although bone erosion is a known feature of this lesion, bone invasion is atypical. This case represents a rare occurrence of an invasive recurrent pleomorphic adenoma.
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spelling doaj.art-f0960ee32b4540b9a6fe34d20d0485d32022-12-22T03:00:34ZengElsevierOral and Maxillofacial Surgery Cases2214-54192022-12-0184100281Invasive recurrent pleomorphic adenoma of the palate: A case report and literature reviewE.N. Nokaneng0Department of Maxillo-Facial and Oral Surgery, Life Fourways Hospital, Johannesburg, South AfricaPleomorphic adenoma (PA) is a salivary gland tumour characterised microscopically by architectural rather than cellular pleomorphism. The neoplasm also has finger-like projections into the pseudocapsule, which clinically has attributed to the high recurrence rate associated with the neoplasm. Vascular and neural invasion have been reported and are regarded as atypical features of the neoplasm. Review of the literature suggests that invasion of bone without malignant transformation by the neoplasm is very rare.A 28-year-old female was diagnosed with an invasive recurrent PA of the palate, which required en-bloc resection of the left maxilla. The computed tomography scan showed a homogeneous, well-defined, multilocular lesion which extended from the anterior to the posterior of the maxilla. The histological analysis did not report any malignant transformation of the lesion. Although bone erosion is a known feature of this lesion, bone invasion is atypical. This case represents a rare occurrence of an invasive recurrent pleomorphic adenoma.http://www.sciencedirect.com/science/article/pii/S2214541922000402BenignNeoplasmRecurrentPleomorphic adenomaAtypical featureBone invasion
spellingShingle E.N. Nokaneng
Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
Oral and Maxillofacial Surgery Cases
Benign
Neoplasm
Recurrent
Pleomorphic adenoma
Atypical feature
Bone invasion
title Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
title_full Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
title_fullStr Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
title_full_unstemmed Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
title_short Invasive recurrent pleomorphic adenoma of the palate: A case report and literature review
title_sort invasive recurrent pleomorphic adenoma of the palate a case report and literature review
topic Benign
Neoplasm
Recurrent
Pleomorphic adenoma
Atypical feature
Bone invasion
url http://www.sciencedirect.com/science/article/pii/S2214541922000402
work_keys_str_mv AT ennokaneng invasiverecurrentpleomorphicadenomaofthepalateacasereportandliteraturereview