Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II

Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II

Endothelial lipase (EL) plays an important physiological role in modulating HDL metabolism. Data suggest that plasma contains an inhibitor of EL, and previous studies have suggested that apolipoprotein A-II (apoA-II) inhibits the activity of several enzymes involved in HDL metabolism. Therefore, we...

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Bibliographic Details
Main Authors:	Uli C. Broedl, Weijun Jin, Ilia V. Fuki, John S. Millar, Daniel J. Rader
Format:	Article
Language:	English
Published:	Elsevier 2006-10-01
Series:	Journal of Lipid Research
Subjects:	high density lipoprotein metabolism apolipoprotein A-II high density lipoprotein containing apolipoprotein A-I but no apolipoprotein A-II high density lipoprotein containing both apolipoprotein A-I and apolipoprotein A-II transgenic mice
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520434066

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