Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells
<p>Abstract</p> <p>Background</p> <p>Thymic involution is a prominent characteristic of an aging immune system. When thymic function is reduced/absent, the peripheral T cell pool is subject to the laws of peripheral T cell homeostasis that favor survival/expansion of T...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-02-01
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| Series: | BMC Immunology |
| Online Access: | http://www.biomedcentral.com/1471-2172/13/8 |